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Comparative study of Botox (R) injection treatment for upper eyelid retraction with 6-month follow-up in patients with thyroid eye disease in the congestive or fibrotic stage
(NATURE PUBLISHING GROUP, 2009)
Aim To compare morphometric data of the eyelid fissure and the levator muscle function (LF) before and up to 6 months after transcutaneous injection with five units of Botox (R) in patients with upper lid retraction (ULR) ...
Anti-fibrotic effect of mycophenolate mofetil on Peyronie’s disease experimentally induced with TGF-β
(2019-01-01)
The aim of the present study was to evaluate the histological, histochemical, and stereological changes caused by mycophenolate mofetil (MMF) on the tunica albuginea of rat penises submitted to an injection of transforming ...
The Role of Cytokines in the Fibrotic Responses in Crohn’s Disease
(Frontiers Research Foundation, 2017-08)
Crohn?s disease is an idiopathic disorder of the gut thought to be caused by a combination<br />of environmental and genetic factors in susceptible individuals. It is characterized by<br />chronic transmural inflammation ...
Objective CT-Based Quantification of Lung Sequelae in Treated Patients With Paracoccidioidomycosis
(Lippincott Williams & Wilkins, 2014-11-01)
This study presents methodology for objectively quantifying the pulmonary region affected by emphysemic and fibrotic sequelae in treated patients with paracoccidioidomycosis. This methodology may also be applied to any ...
TGF-beta and mesenchymal hepatic involvement after visceral leishmaniasis
(SPRINGER, 2009)
The liver involvement in the human visceral leishmaniasis (VL) has been related to parasitism and activated Kupffer cells with further occasional fibrotic alterations, especially after long-term disease without treatment. ...
Histopathology aspects and fibrosis evaluation of bovine naturally infected livers by Fasciola hepatica
(2014-01-01)
Fasciolosis is a zoonotic disease that infects especially ruminants and the liver damages in chronic infection caused by the parasite are very severe. The aim of this study was to evaluate the histopathological findings ...
Response patterns in adventitial layer of Echinococcus granulosus sensu stricto cysts from naturally infected cattle and sheep
(BMC, 2021)
Cystic echinococcosis is a zoonotic disease caused by the metacestode of Echinococcus granulosus sensu lato. The disease is characterized by the development of cystic structures inside viscera of the intermediate host, ...
Contribution of inflammatory pathways to Fabry disease pathogenesis
(Academic Press Inc Elsevier Science, 2017-11)
Lysosomal storage diseases are usually considered to be pathologies in which the passive deposition of unwanted materials leads to functional changes in lysosomes. Lysosomal deposition of unmetabolized glycolipid substrates ...
MCL-1 is modulated in Crohn’s disease fibrosis by miR-29b via IL-6 and IL-8
(Springer, 2017-05)
The miR-29 family is involved in fibrosis in multiple organs, including the intestine where miR-29b facilitates TGF-β-mediated up-regulation of collagen in mucosal fibroblasts from Crohn’s disease (CD) patients. Myeloid ...