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The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-beta-dependent Signaling, and Inhibits TGF-beta-dependent Fibrotic Response in Skeletal Muscles
(American Society for Biochemistry and Molecular Biology, 2012)
Decorin is a small proteoglycan, composed of 12 leucine-rich repeats (LRRs) that modulates the activity of transforming growth factor type β (TGF-β) and other growth factors, and thereby influences proliferation and ...
The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-beta-dependent Signaling, and Inhibits TGF-beta-dependent Fibrotic Response in Skeletal Muscles
(American Society for Biochemistry and Molecular Biology, 2012)
Decorin is a small proteoglycan, composed of 12 leucine-rich repeats (LRRs) that modulates the activity of transforming growth factor type β (TGF-β) and other growth factors, and thereby influences proliferation and ...
Comparative study of Botox (R) injection treatment for upper eyelid retraction with 6-month follow-up in patients with thyroid eye disease in the congestive or fibrotic stage
(NATURE PUBLISHING GROUP, 2009)
Aim To compare morphometric data of the eyelid fissure and the levator muscle function (LF) before and up to 6 months after transcutaneous injection with five units of Botox (R) in patients with upper lid retraction (ULR) ...
Anti-fibrotic effect of mycophenolate mofetil on Peyronie’s disease experimentally induced with TGF-β
(2019-01-01)
The aim of the present study was to evaluate the histological, histochemical, and stereological changes caused by mycophenolate mofetil (MMF) on the tunica albuginea of rat penises submitted to an injection of transforming ...
The Role of Cytokines in the Fibrotic Responses in Crohn’s Disease
(Frontiers Research Foundation, 2017-08)
Crohn?s disease is an idiopathic disorder of the gut thought to be caused by a combination<br />of environmental and genetic factors in susceptible individuals. It is characterized by<br />chronic transmural inflammation ...
Quadriceps strength and endurance in fibrotic idiopathic interstitial pneumonia
(Asian Pacific Society of Respirology, 2014)
Background and objective: Quadriceps muscle dysfunction
is an important contributor to exercise limitation
in chronic obstructive pulmonary disease, but
little is known about skeletal muscle function and its
impact on ...
Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis
(2015)
BackgroundTherapeutic options to treat Non-alcoholic steatohepatitis (NASH) are limited. Mineralocorticoid receptor (MR) activation could play a role in hepatic fibrogenesis and its modulation could be beneficial for NASH. ...
Role of extracellular vesicles in hypoxia-induced hepatic injury in non-alcoholic fatty liver disease
(2020)
Background: Nonalcoholic fatty liver disease (NAFLD) is considered the most common liver disease worldwide. Transition from steatosis to non-alcoholic steatohepatitis (NASH) is a key issue in NAFLD. Observations in patients ...
Objective CT-Based Quantification of Lung Sequelae in Treated Patients With Paracoccidioidomycosis
(Lippincott Williams & Wilkins, 2014-11-01)
This study presents methodology for objectively quantifying the pulmonary region affected by emphysemic and fibrotic sequelae in treated patients with paracoccidioidomycosis. This methodology may also be applied to any ...