Twenty batches of polyvalent antivenom produced at the Instituto Clodomiro Picado were analyzed for turbidity, both before and after freezing-thawing and lyophilization. Eight batches became turbid upon freezing-thawing, ...

Freeze-drying is used to improve the long term stability of pharmaceutical proteins. Sugars and polyols have been successfully used in the stabilization of proteins. However, their use in the development of freeze-dried ...

DNase activity of Costa Rican crotaline snake venoms from the genera Bothrops, Crotalus and Lachesis was quantified by an enzymodiffusion method on agarose/DNA gels containing ethidium bromide. The reaction is detected as ...

La administración parenteral de antivenenos constituye el elemento central en la terapia de los envenenamientos por mordeduras o picaduras de animales ponzoñosos. En América Latina existen laboratorios productores de ...

Liquid and lyophilized samples of Lachesis muta venom were stored at different temperatures and for different periods of time, and analyzed by polyacrylamide gel electrophoresis (PAGE) and immunoelectrophoresis. Only slight ...

Lacteous fat globules with their membranes from human milk and calostrum were studied by scanning and transmission electron microscopy. The first appear as spheroidal structures with some irregularities on the surface. ...

Cryptosporidium, a coccidium described in 1907. causes subclinical infections and diarrhea in many vertebrates including man. It departs from other Cryptosporidiiae in its localization on the brush border of epithelial ...

This study examines the geographic structure of observed trends in key hydrologically relevant variables across the western United States at ⅛° spatial resolution during the period 1950–99. Geographical regions, latitude ...