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Genome profiling of fluoroquinolone-resistant uropathogenic Escherichia coli isolates from Brazil
(2021-01-01)
Urinary tract infections (UTIs) are a major public health concern in both community and hospital settings worldwide. Uropathogenic Escherichia coli (UPEC) is the main causative agent of UTI and increasingly associated with ...
Synthesis of Hybrid Fluoroquinolone-Boron Complexes and Their Evaluation in Cervical Cancer Cell Lines
(Hindawi, 2019-01)
Quinolones are a family of antimicrobial agents that have been used in antibacterial and anticancer chemotherapy. Fluoroquinolone targets DNA gyrase and topoisomerase IV enzymes affecting several cellular processes, like ...
FluoroquinolonasFluoroquinolones
(Universidad de Antioquia, Facultad de MedicinaMedellín, Colombia, 2021)
SAR analysis of new dual targeting fluoroquinolones. Implications of the benzenesulfonyl group
(Bentham Science Publishers, 2012-05)
When a benzenesulfonyl moiety (BS) was bound to the N-piperazinyl ring of antibacterial fluoroquinolones (AMFQs) norfloxacin (NOR) or ciprofloxacin (CIP), the resulting benzenesulfonyl-fluoroquinolone (BSFQs) analogs showed ...
Occurrence, Distribution, and Ecological Risk of Fluoroquinolones in Rivers and Wastewaters
(Society of Environmental Toxicology and Chemistry, 2019-10)
The use of fluoroquinolones for the treatment of infections in humans and animals has increased in Argentina, and they can be found in large amounts in water bodies. The present study investigated the occurrence and ...