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Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver
(1997)
Microsomal lauric acid hydroxylation and fatty acid peroxisomal β-oxidation were studied in hepatic subcellulant preparations from streptozotocin-induced diabetic and diabetic insulin-treated rats. The liver microsomes of ...
Fatty acid 2-hydroxylase deficiency Clinical features and brain iron accumulation
(Lippincott Williams & Wilkins, 2015-03-03)
A 21-year-old woman presented with progressive spastic paraplegia, dysarthria, and strabismus since 7 years of age (video on the Neurology (R) Web site at Neurology.org). Brain MRI disclosed white matter changes and iron ...
Evaluation of chronic omega-3 fatty acids supplementation on behavioral and neurochemical alterations in 6-hydroxydopamine-lesion model of Parkinson`s disease
(ELSEVIER IRELAND LTD, 2010)
Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) have been widely associated to beneficial effects over different neuropathologies, but only a few studies associate them to Parkinson`s disease (PD). Rats were submitted ...
A metabolic circadian clock controls rhythms in immortalized human glioblastoma T98G cells
(Tech Science Press, 2016)
Rat spermatogenic cell membranes contain sphingolipids with nonhydroxy and 2-hydroxy very long chain (C24-32) PUFA. The biosynthesis of such fatty acids requires the expression of very long chain fatty acid elongases (Elovl4 ...
A Novel Sterol Desaturase-Like Protein Promoting Dealkylation of Phytosterols in Tetrahymena thermophila
(American Society For Microbiology, 2011-01)
The gene TTHERM_00438800 (DES24) from the ciliate Tetrahymena thermophila encodes a protein with three conserved histidine clusters, typical of the fatty acid hydroxylase superfamily. Despite its high similarity to sterol ...
Fibronectin modulates the endocannabinoid system through the cAMP/PKA pathway during human sperm capacitation
(Wiley-liss, Div John Wiley & Sons Inc, 2019-02)
Fibronectin (Fn) enhances human sperm capacitation via the cAMP/PKA pathway, and the endocannabinoid system participates in this process. Moreover, Fn has been linked to endocannabinoid system components in different ...