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Oral tolerance attenuates airway inflammation and remodeling in a model of chronic pulmonary allergic inflammation
(ELSEVIER SCIENCE BV, 2009)
We investigated the effects of oral tolerance (OT) in controlling inflammatory response, hyperresponsiveness and airway remodeling in guinea pigs (GP) with chronic allergic inflammation. Animals received seven inhalations ...
Repeated stress reduces mucociliary clearance in animals with chronic allergic airway inflammation
(ELSEVIER SCIENCE BV, 2010)
We evaluated if repeated stress modulates mucociliary clearance and inflammatory responses in airways of guinea pigs (GP) with chronic inflammation. The GP received seven exposures of ovalbumin or saline 0.9%. After 4th ...
Effects of Repeated Stress on Distal Airway Inflammation, Remodeling and Mechanics in an Animal Model of Chronic Airway Inflammation
(KARGERBASEL, 2012)
Background/Aims: Epidemiological studies suggest that stress has an impact on asthmatic exacerbations. We evaluated if repeated stress, induced by forced swimming, modulates lung mechanics, distal airway inflammation and ...
Effects of Repeated Stress on Distal Airway Inflammation, Remodeling and Mechanics in an Animal Model of Chronic Airway Inflammation
(Karger, 2012-01-01)
Background/Aims: Epidemiological studies suggest that stress has an impact on asthmatic exacerbations. We evaluated if repeated stress, induced by forced swimming, modulates lung mechanics, distal airway inflammation and ...
Cigarette smoke modifies and inactivates SPLUNC1, leading to airway dehydration
(Federation of American Societies for Experimental Biology, 2018-12)
Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity and mortality worldwide. Cigarette smoke (CS) exposure, a major cause of COPD, dysregulates airway epithelial ion transport and diminishes airway ...
Salbutamol improves markers of epithelial function in mice with chronic allergic pulmonary inflammation
(ELSEVIER SCIENCE BV, 2011)
We investigated the effects of salbutamol on the markers of epithelial function in a murine model of chronic allergic pulmonary inflammation by recording the ciliary beat frequency (CBF) and the transepithelial potential ...
Preventive and curative glycoside kaempferol treatments attenuate the TH2-driven allergic airway disease
(ELSEVIER SCIENCE BV, 2009)
Asthma is a chronic respiratory disease characterized by airway inflammation and airway hyperresponsiveness (AHR). One strategy to treat allergic diseases is the development of new drugs. Flavonoids are compounds derived ...
Animal models in chronic obstructive pulmonary disease-an overview
(Informa Healthcare, 2014-08-01)
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airway obstruction resultant from an augmented inflammatory response of the respiratory tract to noxious particles and gases. Previous reports ...
Role of the Fungus Pneumocystis in IL1β Pathway Activation and Airways Collagen Deposition in Elastase-Induced COPD Animals
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)