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Modulation of (Na,K)-ATPase activity by membrane fatty acid composition: Therapeutic implications in human hypertension
(2014)
Oxidative stress (OS) plays a key role in the pathophysiology of essential hypertension and is associated with changes in the cell membrane fatty acid composition and fluidity. As (Na,K)-ATPase is modulated by the surrounding ...
Relationship between (Na + K)-ATPase activity, lipid peroxidation and fatty acid profile in erythrocytes of hypertensive and normotensive subjects
(2007)
Oxidative stress may play a role in the pathogenic mechanism of essential hypertension. Lipid peroxidation can alter the cellular structure of membrane-bound enzymes by changing the membrane phospholipids fatty acids ...
11β-hydroxysteroid dehydrogenase type-2 and type-1 (11β-HSD2 and 11β-HSD1) and 5β-reductase activities in the pathogenia of essential hypertension
(2010)
Cortisol availability is modulated by several enzymes: 11β-HSD2, which transforms cortisol (F) to cortisone (E) and 11β-HSD1 which predominantly converts inactive E to active F. Additionally, the A-ring reductases (5α- and ...
A comparison of the effects of the selective peripheral α1-blocker terazosin with the selective β1-blocker atenolol on blood pressure, exercise performance and the lipid profile in mild-to-moderate essential hypertension
(Springer-Verlag, 1992)
The effects of six weeks of treatment with the selective peripheral α1-adrenoceptor blocker terazosin, or the selective β1-adrenoceptor blocker atenolol on blood pressure, exercise performance and blood lipid profile were ...
Comparison of extra renal potassium disposal in hypertensive, diabetic and normal subjects Estudio comparativo del manejo extrarrenal de potasio en sujetos controles, pacientes hipertensos y diabéticos
(1997)
Background: Sodium and potassium ions are involved in the regulation of blood pressure and the genesis of hypertension. Aim: To assess internal potassium balance, as a measure of sodium pump activity, in subjects with ...
Relationship between (Na plus K)-ATPase activity, lipid peroxidation and fatty acid profile in erythrocytes of hypertensive and normotensive subjects
(2007)
Oxidative stress may play a role in the pathogenic mechanism of essential hypertension. Lipid peroxidation can alter the cellular structure of membrane-bound enzymes by changing the membrane phospholipids fatty acids ...
Morbidity and mortality of essential arterial hypertension treated in Chile: a 15 years' follow-up study Morbimortalidad de la hipertensión arterial esencial tratada en Chile: seguimiento a 15 años.
(1991)
In order to establish morbidity and mortality in treated patients with essential hypertension, a prospective study was started in 1974. 714 patients were followed for 15 years. Admission criteria included diastolic blood ...
The Expression of RAC1 and Mineralocorticoid Pathway- Dependent Genes are Associated With Different Responses to Salt Intake
(Oxford University Press, 2015)
BACKGROUND
Rac1 upregulation has been implicated in salt-sensitive hypertension as a modulator of mineralocorticoid receptor (MR) activity. Rac1 could affect the expression of oxidative stress markers, such as ...
Effect of Carvedilol and Nebivolol on Oxidative Stress-related Parameters and Endothelial Function in Patients with Essential Hypertension
(2012)
Oxidative stress and endothelial dysfunction have been associated with essential hypertension (EH) mechanisms. The purpose of this study was to evaluate the effect of carvedilol and nebivolol on the oxidative stress-related ...
Efecto del polimorfismo del receptor ? 2 adrenérgico sobre la respuesta antihipertensiva en pacientes con hipertensión esencial
(Universidad de Antioquia, Facultad de MedicinaMedellín, Colombia, 2022)