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Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines
(Baishideng Publishing Group, 2014-07)
Neuregulin-1 (NRG1) signaling through the tyrosine kinase receptors erbB2 and erbB4 is required for cardiac morphogenesis, and it plays an essential role in maintaining the myocardial architecture during adulthood. The ...
The role of the Neuregulin-1/Erbb signaling pathway in cardiac morphogenesis and remodeling
(Sociedad Argentina de Fisiología, 2014-02)
Neuregulin-1 (NRG1) signaling through tyrosine kinase receptors erbB2 and erbB4 was revealed essential for cardiac development as mouse mutated in the Nrg1 or either cognate receptors Erbb2 or Erbb4 genes lack the formation ...
ErbB receptors and fatty acid synthase expression in aggressive head and neck squamous cell carcinomas
(Wiley-blackwellMaldenEUA, 2010)
Definición de una nueva clase de complejo transcripcional: ErbB2 actúa de coactivador de Stat3 promoviendo la proliferación en tumores mamariosDefining a new class of transcriptional complex: ErbB2 acts as coactivator of Stat3 inducing proliferation in breast tumors
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2010)
Expressão da proteína erbB-3/HER3 em câncer de pulmão pela técnica de imuno-histoquímica e sua correlação com características clínicopatológicas
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2008)
Four members belong to the erbB family, erbB1, erbB2, erbB3, and erbB4. Several reports have investigated the expression of members from this family, however with only few regarding to the role of erbB3 on non-small cell ...
Progesterone Receptor Induces ErbB-2 Nuclear Translocation To Promote Breast Cancer Growth via a Novel Transcriptional Effect: ErbB-2 Function as a Coactivator of Stat3
(American Society For Microbiology, 2010-12)
Progesterone receptor (PR) and ErbB-2 bidirectional cross talk participates in breast cancer development. Here, we identified a new mechanism of the PR and ErbB-2 interaction involving the PR induction of ErbB-2 nuclear ...
Activation of ErbB-2 via a hierarchical interaction between ErbB-2 and type I insulin-like growth factor receptor in mammary tumor cells.
(Nature Publishing Group, 2001-01)
The present study focused on interactions between signaling pathways activated by progestins and by type I and II receptor tyrosine kinases (RTKs) in mammary tumors. An experimental model in which the synthetic progestin ...