Buscar
Mostrando ítems 1-10 de 742
The UPRosome-decoding novel biological outputs of IRE1 alpha function
(Company Biologists, 2020)
Different perturbations alter the function of the endoplasmic reticulum (ER), resulting in the accumulation of misfolded proteins in its lumen, a condition termed ER stress. To restore ER proteostasis, a highly conserved ...
Progesterone, estrogen (er-alpha and er-beta), and oxytocin receptor gene expression in canine embryos
(CSIRO Publishing, 2013-01-01)
Expression and regulation of the estrogen receptors in PC-3 human prostate cancer cells
(Elsevier Science Inc, 2016)
The aim of this study was to identify the expression, cellular localization and regulation of classic estrogen receptors ER alpha, and ER beta, ER-alpha 36 isoform and GPER in the androgen-independent prostate cancer cell ...
Structure-Based Approach for the Study of Estrogen Receptor Binding Affinity and Subtype Selectivity
(AMER CHEMICAL SOC, 2008)
Estrogens exert important physiological effects through the modulation of two human estrogen receptor (hER) subtypes, alpa (hER alpha) and beta (hER beta). Because the levels and relative proportion of hER alpha and hER ...
Effects of estrogen receptor alpha and beta gene deletion on estrogenic induction of progesterone receptors in the locus coeruleus in female mice
(HUMANA PRESS INC, 2009)
Locus coeruleus (LC) is involved in the LHRH regulation by gonadal steroids. We investigated the expression of progesterone and estrogen receptors (PR; ER) in LC neurons of ER alpha (alpha ERKO) or ER beta (beta ERKO) ...
Fine-tuning ER stress signal transducers to treat amyotrophic lateral sclerosis
(Frontiers Media SA, 2017)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motoneurons and paralysis. The mechanisms underlying neuronal degeneration in ALS are starting to be elucidated, ...
(off) Targeting UPR signaling: the race toward intervening ER proteostasis
(Taylor & Francis, 2018)
(off)Targeting UPR signaling: the race toward intervening ER proteostasis
(Taylor and Francis Ltd, 2018)
Interplay between the oxidoreductase pdia6 and microrna-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis
(AMER ASSOC ADVANCEMENT SCIENCE, 2014)
The disruption of the energy or nutrient balance triggers endoplasmic reticulum (ER) stress, a process that mobilizes various strategies, collectively called the unfolded protein response (UPR), which reestablish homeostasis ...
Profiling of gene expression regulated by 17 beta-estradiol and tamoxifen in estrogen receptor-positive and estrogen receptor-negative human breast cancer cell lines
One area of great importance in breast cancer (BC) research is the study of gene expression regulated by both estrogenic and antiestrogenic agents. Although many studies have been performed in this area, most of them have ...