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Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell lines overexpressing Egr-1
(Spandidos Publications, 2014)
The present study examined the effect of the overexpression of early growth response gene (Egr-1) on transforming growth factor β-1 (TGF-β1) and p14ARFlevels, in PC-3 and LNCaP prostate carcinoma cell lines. Amplification ...
The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines
(2010)
We have examined the effects of a siRNA targeting the Egr-1, alone or in combination with the breast cancer therapeutic camptothecin (Cpt), in suppressing breast cancer cell survival and anchorage-independent growth in the ...
Increased expression of p21Waf1/Cip1 and JNK with costimulation of prostate cancer cell activation by an siRNA Egr-1 inhibitor
(2013)
The p21Waf1/Cip1 protein (hereafter, p21) and the c‑Jun N-terminal kinase (JNK) are two well-characterized cell modulators that play a crucial role in cell differentiation, senescence and apoptosis. Here, we report that ...
Inhibition of Egr-1 by siRNA in prostate carcinoma cell lines is associated with decreased expression of AP-1 and NF-κB
(2011)
Previous studies suggest that the effects of Egr-1 on tumorigenesis are critically dependent on the levels of Egr-1 and the cellular context. For this reason, we examined the effects of blocking the Egr-1 activity by a ...
Novelty, but Not Operant Aversive Learning, Enhances Fos and Egr-1 Expression in the Medial Prefrontal Cortex and Hippocampal Areas of Rats
(AMER PSYCHOLOGICAL ASSOCWASHINGTON, 2012)
Immediate early genes (IEG) are presumed to be activated in response to stress, novelty, and learning. Evidence supports the involvement of prefrontal and hippocampal areas in stress and learning, but also in the detection ...
Strategies for emission control in diesel engine to meet Euro VI
(Elsevier Sci LtdOxfordInglaterra, 2013)
Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity
(Sociedad de Biología de Chile, 2005)
Genome-wide identification of multifunctional laccase gene family in Eucalyptus grandis: potential targets for lignin engineering and stress tolerance
(2020-06-01)
Key message: A survey of theEucalyptus grandis genome revealed the presence of 54 laccase genes. Their tissue-specific and stress-induced expression patterns suggest a role in lignification and adaptation to abiotic stresses. ...
Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity
(Society of Biology of Chile, 2005)
The specific signaling connections between the mitogen-activated protein kinases (MAPK) such as c-Jun N-terminal kinase (JNK-1) and phosphatases PP4 and M3/6, affecting the family of early nuclear factors, is complex and ...