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Estudos sobre liberação controlada e vetorização de drogas através de lipossomas
The text highlights the state of research related with the application of liposomes in the control of drug delivery and drug target to infectious diseases. Liposomes have several pharmaceutical applications and this ...
Sistemas biodegradáveis contendo acetato de prednisolona para administração orbitária
Purpose: The present study aimed to evaluate an injectable extended-release formulation of prednisolone acetate (PA) for orbital administration. Methods: Microspheres (MEs) of poly-ε-caprolactone (PCL) containing PA were ...
Liposomes and micro/nanoparticles as colloidal carriers for nasal drug delivery
The use of the nasal route for drug delivery has attracted much interest in recent years in the pharmaceutical field. Local and principally systemic drug delivery can be achieved by this route of administration. But the ...
Colloidal carriers for ophthalmic drug delivery
(Bentham Science Publ Ltd, 2005-05-01)
To achieve effective drug concentration at the intended site for a sufficient period of time is a requisite desired for many drug formulations. For drugs intended to ocular delivery, its poor bioavailability is due to ...
Development and in vitro evaluation of coated pellets containing chitosan to potential colonic drug delivery
In this work pellets containing chitosan for colonic drug delivery were developed. The influence of the polysaccharide in the pellets was evaluated by swelling, drug dissolution and intestinal permeation studies. Drug-loaded ...
Advances in prodrug design
The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...