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Antioxidants and biomarkers of oxidative damage in the saliva of patients with Down's syndrome
(Elsevier B.V., 2015-04-01)
Background: The aim of this study was to investigate enzymatic and non-enzymatic antioxidant systems and levels of biomarker levels of oxidative damage in the saliva of patients with Down's syndrome (DS).Methods: ...
Functional activity of neutrophils and systemic inflammatory response of Down's syndrome patients with periodontal disease
(2012-07-01)
Periodontal disease (PD) is characterized as an inflammatory process that compromises the support and protection of the periodontium. Patients with Down's syndrome (DS) are prone to develop PD. Neutrophils (NE) are the ...
Functional activity of neutrophils and systemic inflammatory response of Down's syndrome patients with periodontal disease
(2012-07-01)
Periodontal disease (PD) is characterized as an inflammatory process that compromises the support and protection of the periodontium. Patients with Down's syndrome (DS) are prone to develop PD. Neutrophils (NE) are the ...
Nutritional Status of Zinc in Children with Down Syndrome
(HUMANA PRESS INC, 2010)
Experimental and clinical studies have established that zinc metabolism is altered in individuals with Down syndrome (DS). The present study intends to evaluate the nutritional status of zinc in children with DS by determining ...
Reduced salivary flow rate and high levels of oxidative stress in whole saliva of children with Down syndrome
(2017-11-01)
Aim: To investigate salivary parameters between children with Down Syndrome (DS) and without DS. Materials and Methods: Stimulated whole saliva was collected from 18 children with DS and 23 without DS. Salivary flow rate, ...
Adaptive downregulation of mitochondrial function in down syndrome.
(Elsevier, 2013-01-08)
Mitochondrial dysfunction and oxidative stress are common features of Down syndrome (DS). However, the underlying mechanisms are not known. We investigated the relationship between abnormal energy metabolism and oxidative ...
Polymorphisms of interleukin 6 in Down syndrome individuals: a case-control study
(Funpec-editora, 2017-08-18)
Down syndrome (DS) individuals present impaired adaptive immune system. However, the etiology of the immunological deficiency in these individuals is not completely understood. This study investigated the frequency of ...
Trastornos neurológicos en niños con síndrome de Down
(SOC MEDICA SANTIAGO, 2012)
Background: Neurological disturbances are common problems in children with Down Syndrome (DS). Aim: To determine the prevalence of neurological disorders affecting children with Down Syndrome. Patients and Methods: Review ...
Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated Kinase (PAK) Activity in an In Vitro Neuronal Model of Down Syndrome: Consequences on Cell Process Formation and Extension
(Springer New York LLC, 2016)
© 2016, Springer Science+Business Media New York.In humans, Down syndrome (DS) is caused by the presence of an extra copy of autosome 21. The most striking finding in DS patients is intellectual disability and the onset ...