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Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine
(Elsevier Science, 2012-07)
Endogenous renal dopamine is a major physiological regulator of renal ion transport; however its intracellular signaling pathways are not thoroughly understood. The present study examined the role of 20-hydroxyeicosatetraenoic ...
Behavioral effects of triadimefon in zebrafish are associated with alterations of the dopaminergic and serotonergic pathways
(Elsevier, 2019)
Triadimefon (TDF) is a triazole fungicide extensively used in agriculture that has been found as a pollutant in numerous water sources. In mammals, it inhibits monoamine uptake through binding to the dopamine transporter, ...
A catecholamine transporter from the human parasite Schistosoma mansoni with low affinity for psychostimulants
(ELSEVIER SCIENCE BV, 2011)
The trematode Schistosoma mansoni is the primary cause of schistosomiasis, a devastating neglected tropical disease that affects 200 million individuals. Identifying novel therapeutic targets for the treatment of schistosomiasis ...
Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues
(2022-01-01)
Dopamine is an important neurotransmitter that regulates numerous essential functions, including cognition and voluntary movement. As such, it serves as an important scaffold for synthesis of novel analogues as part of ...
Atrial natriuretic peptide stimulates dopamine tubular transport by organic cation transporters: A novel mechanism to enhance renal sodium excretion
(Public Library of Science, 2016-07)
The aim of this study was to demonstrate the effects of atrial natriuretic peptide (ANP) on organic cation transporters (OCTs) expression and activity, and its consequences on dopamine urinary levels, Na+ ,K+ -ATPase ...
Urodilatin regulates renal dopamine metabolism
(Società Italiana di Nefrologia, 2013-05)
Sodium and water transport across renal proximal tubules is regulated by diverse hormones such as dopamine and urodilatin. We have previously reported that urodilatin stimulates extraneuronal dopamine uptake in external ...
Cognitive and olfactory deficits in Machado-Joseph disease: A dopamine transporter study
(Elsevier B.V., 2012-08-01)
Cognitive and olfactory impairments have been demonstrated in patients with Machado-Joseph disease (MJD), and a possible relationship with dopaminergic dysfunction is implicated. However, there is still controversy regarding ...