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Nicotinamidase/pyrazinamidase of Mycobacterium tuberculosis forms homo-dimers stabilized by disulfide bonds
(Elsevier, 2014)
Recombinant wild-pyrazinamidase from H37Rv Mycobacterium tuberculosis was analyzed by gel electrophoresis under differential reducing conditions to evaluate its quaternary structure. PZAse was fractionated by size exclusion ...
Inhibition of arenavirus infection by thiuram and aromatic disulfides
(Elsevier Science, 2010-09)
A selected group of aromatic disulfides, thiuram disulfides and thiosulfones, provided by the National Cancer Institute, were evaluated in vitro for their inhibitory activity against Junin virus (JUNV), the causative agent ...
Rewiring Chemical Networks Based on Dynamic Dithioacetal and Disulfide Bonds
(Wiley VCH Verlag, 2018-03-23)
The control of the connectivity between nodes of synthetic networks is still largely unexplored. To address this point we take advantage of a simple dynamic chemical system with two exchange levels that are mutually connected ...
Heparin enhances protamine disulfide bond reduction during in vitro decondensation of human spermatozoa
(Oxford University Press, 2012-05-02)
BACKGROUND: Human sperm nuclear decondensation in vivo involves protamine disulfide bond reduction by glutathione (GSH) and protamine/histone exchange, presumably with heparan sulfate (HS) as the protamine acceptor. The ...
Mechanochemical disulfide reduction reveals imprints of noncovalent sulfur⋯oxygen chalcogen bonds in protein-inspired mimics in aqueous solution
(Royal Society of Chemistry, 2020-11)
The surprisingly rich chemistry of mechanically activated cleavage of disulfide bonds has been uncovered only recently. Using a disulfide protein mimic together with Cleland's reagent (DTT) as the attacking nucleophile in ...
Robust Binding of Disulfide-Substituted Rhenium Bipyridyl Complexes for CO2 Reduction on Gold Electrodes
(Frontiers Media S.A., 2020-02)
Heterogenization of homogenous catalysts on electrode surfaces provides a valuable approach for characterization of catalytic processes in operando conditions using surface selective spectroelectrochemistry methods. Ligand ...
Mode of inactivation of arenaviruses by disulfide-based compounds
(Elsevier Science, 2002-12)
Several disulfide-based compounds, including intermolecular aromatic disulfides of the type Ph-S-S-Ph and dithianes with the sulfur atoms tethered in a ring structure, have shown effective inhibitory activity against the ...
Density functional theory study of the oxidation reaction in the gas and aqueous phase of allyl methyl disulfide with hydroxyl radical
(Springer/Plenum Publishers, 2019-02)
An in silico analysis of the oxidation mechanism of allyl methyl disulfide (AMDS) by hydroxyl radical was achieved at DFT level using B3LYP, CAM-B3LYP, M06-2X, and BMK functionals and 6-311++G(3df,2p) triple-zeta basis ...
Computational study of the hydrogen peroxide scavenging mechanism of allyl methyl disulfide, an antioxidant compound from garlic
(Springer, 2019-11)
Although many sulfur containing garlic compounds present antioxidant activity, little is known about molecular mechanisms through which these compounds react with reactive oxygen species. In this work, the reactivity and ...
Devulcanization of natural rubber industry waste in supercritical carbon dioxide combined with diphenyl disulfide
(Pergamon-Elsevier Science Ltd, 2020-12)
The elimination of rubber wastes without affecting the environment is one of the most important challenges of the 21st century waste management. Accordingly, the present work is focused on the recycling of natural rubber ...