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Tryptophan oxidation by singlet molecular oxygen [O-2 ((1)Delta(g))]: Mechanistic studies using O-18-labeled hydroperoxides, mass spectrometry, and light emission measurements
(AMER CHEMICAL SOC, 2008)
Proteins have been considered important targets for reactive oxygen species. Indeed, tryptophan (W) has been shown to be a highly susceptible amino acid to many oxidizing agents, including singlet molecular oxygen [O-2 ...
Oxidation and nitration of ribonuclease and lysozyme by peroxynitrite and myeloperoxidase
(ELSEVIER SCIENCE INC, 2009)
In spite of the many studies on protein modifications by reactive species, knowledge about the products resulting from the oxidation of protein-aromatic residues, including protein-derived radicals and their stable products, ...
Characterization of O(2) ((1)Delta(g))-Derived Oxidation Products of Tryptophan: A Combination of Tandem Mass Spectrometry Analyses and Isotopic Labeling Studies
(ELSEVIER SCIENCE INC, 2009)
The fragmentation mechanisms of singlet oxygen [O(2) ((1)Delta(g))]-derived oxidation products of tryptophan (W) were analyzed using collision-induced dissociation coupled with (18)O-isotopic labeling experiments and ...
Concatemerization increases the inhibitory activity of short, cell-penetrating, cationic and tryptophan-rich antifungal peptides
(Springer, 2015-04)
There are short cationic and tryptophan-rich antifungal peptides such as the hexapeptide PAF26 (RKKWFW) that have selective toxicity and cell penetration properties against fungal cells. This study demonstrates that ...
Methods for the detection of reactive oxygen species employed in the identification of plant photosensitizers
(Academic Press Inc Elsevier Science, 2016-10)
Over the past ten years, alternative methods for the rapid screening of PSs have been developed. In the present work, a study was undertaken to correlate the phototoxicity of plant extracts on either prokaryotic or eukaryotic ...
Properties of two apyrases from Solanum tuberosum
(1982)
Two homogeneous isoenzymes of apyrase from Pimpernel and Desirée varieties of Solanum tuberosum were obtained by affinity chromatography on agarose-Cibacron Blue or agarose-ATP-phosphonate columns. Both enzymes split POP ...
Relation between polyphenol profile and antioxidant capacity of different Argentinean wheat varieties. A boosted regression trees study
(Elsevier, 2017-03)
We report the polyphenol profile and antioxidant capacity (AC) of 12 Argentinean wheat varieties from different regions. The polyphenol profile was studied by HPLC–MS. The AC was measured by TEAC and FRAP. Twenty-five ...
Mecanismos de ação e controle da digestão de proteínas e peptídios em humanos
(1999-12-01)
This review aims to report the major control mechanisms of protein and peptides digestion of special interest in human patients. Regarding protein assimilation its digestive process begins at the stomach with some not so ...