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Differential processing in modality-specific Mauthner cell dendrites
(Wiley Blackwell Publishing, Inc, 2017-12)
Key points: The present study examines dendritic integrative processes that occur in many central neurons but have been challenging to study in vivo in the vertebrate brain. The Mauthner cell of goldfish receives auditory ...
A computational model on the goldfish Mauthner cell.
(BioMed Central, 2014-07)
Integration of multimodal information is of key importance to generate adaptive behavior. However, our understanding of how multimodal integration is implemented at the dendritic level is still scant. We address this ...
Mechanisms regulating dendritic arbor patterning
(Springer, 2017-12)
The nervous system is populated by diverse types of neurons, each of which has dendritic trees with strikingly different morphologies. These neuron-specific morphologies determine how dendritic trees integrate thousands ...
Dendritic cell maturation and cross-presentation: timing matters!
(Wiley Blackwell Publishing, Inc, 2016-07)
As a population, dendritic cells (DCs) appear to be the best cross-presenters of internalized antigens on major histocompatibility complex class I molecules in the mouse. To do this, DCs have developed a number of unique ...
Lrig1 is a cell-intrinsic modulator of hippocampal dendrite complexity and BDNF signaling
(Nature Publishing Group, 2016-04)
Even though many extracellular factors have been identified as promoters of general dendritic growth and branching, little is known about the cell-intrinsic modulators that allow neurons to sculpt distinctive patterns of ...
CD1a- and CD83-positive dendritic cells as prognostic markers of metastasis development in early breast cancer patients
(Springer Tokyo, 2021-06)
Dendritic cells (DCs) are the most potent antigen-presenting cells that play a major role in initiating the antitumor immune response in different types of cancer. However, the prognostic significance of the accumulation ...
Monocyte-derived dendritic cells early exposed to Mycobacterium tuberculosis induce an enhanced T helper 17 response and transfer mycobacterial antigens.
(Elsevier Gmbh, 2016-06)
Tuberculosis (TB) is a complex disease, and the success of the bacterium depends on its ability to evade the immune response. Previously, we determined that Mycobacterium tuberculosis (Mtb) impairs the function of dendritic ...
Pulsing Dendritic Cells with Whole Tumor Cell Lysates
(Springer, 2014-03)
One of the strategies employed in immunotherapy for cancer is to use of ex vivo-generated dendritic cells (DC) pulsed with tumor antigens. Several approaches have been used to obtain and load tumor antigens in DC. One such ...
Update on the Functionality of Thymic Stromal Lymphopoietin and its Interaction with Dendritic Cells, to Trigger a Pro or Anti-Inflammatory Status
(SciTech Central Inc., 2020-11)
Thymic stromal lymphopoietin (TSLP) is a cytokine produced primarily by activated epithelial cells of the lung, skin and intestine. The foremost property of this cytokine is to condition dendritic cells (DC) to initiate ...
Normal mitral cell dendritic development in the setting of Mecp2 mutation
(Pergamon-Elsevier Science Ltd, 2012-01)
Rett syndrome (RTT) is an autism spectrum disorder caused by mutation in the gene encoding methyl CpG binding protein 2 (MECP2). Evidence to date suggests that these disorders display defects in synaptic organization and ...