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Influence of Darunavir: β-cyclodextrin complex on the solubility of Darunavir
(2014)
Darunavir, a protease inhibitor used in the treatment of HIV infection, was complexed with β-cyclodextrin because of its low solubility in water and poor bioavailability, with the objective of improving the solubility of ...
Complexation between darunavir ethanolate and beta cyclodextrin: experimental and theoretical studies
(2014)
Darunavir (DRV) is a protease inhibitor used in the treatment of HIV infection, which constitutes a keystone in the therapy of patients infected with this virus. Unfortunately, DRV has low solubility in water and poor ...
Complexation between darunavir and β-Cyclodextrin. Experimental and theoretical studies
(World Journal of Pharmacy and Pharmaceutical Sciences, 2014-06)
Darunavir (DRV) is a protease inhibitor used in the treatment of HIVinfection, which constitutes a keystone in the therapy of patientsinfected with this virus. Unfortunately, DRV has low solubility inwater and poor ...
Análise quimico-farmacêutica de Darunavir etanolato em comprimidos e de seu complexo de inclusão
(Universidade Estadual Paulista (Unesp), 2015-04-07)
The work aimed the formation of complex darunavir:β-cyclodextrin and the study of the consequences of complexation, as well as development and validation of analytical methods for qualitative and quantitative determination ...
Recent advances in the study of the inclusion complex darunavir-β-cyclodextrin by LC-MS
(2016-05-01)
Darunavir is a protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection. This work proposes a LC-MS method indicative of stability for the determination of darunavir in the complex ...
Análise quimico-farmacêutica de Darunavir etanolato em comprimidos e de seu complexo de inclusão
(Universidade Estadual Paulista (UNESP), 2015)