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Effect of lycopene on doxorubicin-induced cardiotoxicity: An echocardiographic, histological and morphometrical assessment
(Blackwell Publishing, 2007-07-01)
Doxorubicin is an excellent chemotherapeutic agent utilized for several types of cancer but the irreversible doxorubicin-induced cardiac damage is the major limitation for its use. Oxidative stress seems to be associated ...
Effect of lycopene on doxorubicin-induced cardiotoxicity: An echocardiographic, histological and morphometrical assessment
(Blackwell Publishing, 2007-07-01)
Doxorubicin is an excellent chemotherapeutic agent utilized for several types of cancer but the irreversible doxorubicin-induced cardiac damage is the major limitation for its use. Oxidative stress seems to be associated ...
Doxorubicin as an antioxidant: Maintenance of myocardial levels of lycopene under doxorubicin treatment
(Elsevier B.V., 2007-09-01)
The mechanism of doxorubicin-induced cardiotoxicity remains controversial. Wistar rats (n=96) were randomly assigned to a control (C), lycopene (L), doxorubicin (D), or doxorubicin+lycopene (DL) group. The L and DL groups ...
Doxorubicin as an antioxidant: Maintenance of myocardial levels of lycopene under doxorubicin treatment
(Elsevier B.V., 2007-09-01)
The mechanism of doxorubicin-induced cardiotoxicity remains controversial. Wistar rats (n=96) were randomly assigned to a control (C), lycopene (L), doxorubicin (D), or doxorubicin+lycopene (DL) group. The L and DL groups ...
Carnitine partially improves oxidative stress, acrosome integrity, and reproductive competence in doxorubicin-treated rats
(Wiley, 2018)
Doxorubicin has been largely used in anticancer therapy in adults, adolescents, and children. The efficacy of l-carnitine as an antioxidant substance has been confirmed both in humans and rats. Carnitine, present in testis ...
Exercise preconditioning modulates genotoxicity induced by doxorubicin in multiple organs of rats
(Wiley-Blackwell, 2012-06-01)
The aim of this study was to investigate the effects of exercise in multiple organs of rats treated with doxorubicin. Male adult Wistar rats were distributed into the following groups: sedentary + NaCl; exercise + NaCl; ...
Exercise preconditioning modulates genotoxicity induced by doxorubicin in multiple organs of rats
(Wiley-Blackwell, 2012-06-01)
The aim of this study was to investigate the effects of exercise in multiple organs of rats treated with doxorubicin. Male adult Wistar rats were distributed into the following groups: sedentary + NaCl; exercise + NaCl; ...
Late morfofunctional alterations of the Sertoli cell caused by doxorubicin administered to prepubertal rats
(Biomed Central Ltd., 2014)
Matrix metalloproteinases 2 and 9 in rabbits with doxorubicin-induced cardiomyopathy
(2018-02-01)
Some studies have shown the role played by matrix metalloproteinases and their inhibitors in doxorubicin cardiotoxicity. In this study, we sought to investigate how plasma and myocardial MMP 2 and 9 perform in rabbits with ...
Carnitine partially protects the rat testis against the late damage produced by doxorubicin administered during pre-puberty
(Wiley-Blackwell, 2014-11-01)
Doxorubicin, an anticancer drug, is widely included in chemotherapy protocols to combat childhood cancer. Carnitine, an important quaternary amine, is present in testis and epididymis and is involved in sperm maturation; ...