Now showing items 1-10 of 45
Mechanistic insight of the photodynamic inactivation of Escherichia coli by a tetracationic zinc(II) phthalocyanine derivative
(Elsevier Science, 2009-03)
Photodynamic inactivation (PDI) of Escherichia coli has been studied in cultures treated with zinc(II) 2,9,16,23-tetrakis[4-(N-methylpyridyloxy)]phthalocyanine (ZnPPc+4) to obtain insight about the mechanism of damage. ...
ERIC-PCR technique applied to monitoring and quantification of DNA damage during water disinfection process
(Elsevier Science Sa, 2019-11)
In this work, we propose a novel application of ERIC-PCR technique to study DNA damage after ultraviolet radiation (UV) and peracetic acid (PAA) treatment for water disinfection purpose. The efficacy of both treatments on ...
Mechanistic aspects of the photodynamic inactivation of Candida albicans induced by cationic porphyrin derivatives
(Elsevier France-editions Scientifiques Medicales Elsevier, 2012-12)
Photodynamic inactivation of Candida albicans produced by 5-(4-trifluorophenyl)-10,15,20-tris(4-N,N,N-trimethylammoniumphenyl)porphyrin (TFAP3+), 5,10,15,20-tetrakis(4-N,N,N-trimethylammoniumphenyl) porphyrin (TMAP4+) and ...
Phenotypic resistance in photodynamic inactivation unravelled at the single bacterium level
(American Chemical Society, 2019-07-09)
Herein we report a simple fluorescence microscopy methodology that, jointly with four photosensitizers (PSs) and a cell viability marker, allows monitoring of phenotypic bacterial resistance to photodynamic inactivation ...
Epigenetic inactivation of mir-203 as a key step in neural crest epithelial-to-mesenchymal transition
(Company of Biologists, 2019-04)
miR-203 is a tumor-suppressor microRNA with known functions in cancer metastasis. Here, we explore its normal developmental role in the context of neural crest development. During the epithelial-to-mesenchymal transition ...
Photodegradation and phototoxicity of antibacterial agents and the new alternatives for the photo-inactivation of microorganisms
(Facultad Experimental de Ciencias de la Universidad del Zulia, 2011)
Hypermutation in burkholderia cepacia complex is mediated by DNA mismatch repair inactivation and is highly prevalent in cystic fibrosis chronic respiratory infection
(Elsevier Gmbh, 2014-08)
The Burkholderia cepacia complex (Bcc) represents an important group of pathogens involved in long-term lung infection in cystic fibrosis (CF) patients. A positive selection of hypermutators, linked to antimicrobial ...
A DNA vaccine formulated with chemical adjuvant provides partial protection against bovine herpes virus infection in cattle
(Frontiers Research Foundation, 2017-01)
Bovine herpesvirus-1 (BoHV-1) is the causative agent of bovine infectious rhinotracheitis, an important disease worldwide. Although conventional BoHV-1 vaccines, including those based on the use of modified live virus and ...
Inactivation of tyrosinase photoinduced by pterin
(Academic Press Inc Elsevier Science, 2012-08)
Tyrosinase catalyzes in mammals the first and rate-limiting step in the biosynthesis of the melanin, the main pigment of the skin. Pterins, heterocyclic compounds able to photoinduce oxidation of DNA and its components, ...
Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation
(Humana Press, 2019-03)
Chronic metabolic alterations may represent a risk factor for the development of cognitive impairment, dementia, or neurodegenerative diseases. Hyperglycemia and obesity are known to imprint epigenetic markers that compromise ...