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A DNA BINDING COMPOUND FROM PROSOPIS TAMARUGO PODS
(Sociedad Chilena de Química, 2000)
A DNA binding compound from Prosopis tamarugo pods
(Sociedad Chilena de Quimica, 2007)
DNA binding, topoisomerase inhibition and cytotoxicity of palladium(II) complexes with 1,10-phenanthroline and thioureas
(2016-05-01)
Metallointercalators represent a promising alternative in cancer chemotherapy. We present herein DNA binding, topoisomerase inhibition and cytotoxic studies on a series of complexes of general formulae [Pd(phen)(tu∗)2]2+ ...
Effect of 3,4-ethylenedioxy-extension of thiophene core on the DNA/RNA binding properties and biological activity of bisbenzimidazole amidines
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Novel bisbenzimidazoles (4-6), characterized by 3,4-ethylenedioxy-extension of thiophene core, revealed pronounced affinity and strong thermal stabilization effect toward ds-DNA. They interact within ds-DNA grooves as ...
DNA binding alkaloids from Lobelia bridgesii hook et arn and Lobelia tupa L
(Sociedad Chilena de Quimica, 2007)
Inhibition of human DNA topoisomerase IB by nonmutagenic ruthenium(II)-based compounds with antitumoral activity
(2016-02-01)
Herein we synthesized two new ruthenium(ii) compounds [Ru(pySH)(bipy)(dppb)]PF6 (1) and [Ru(HSpym)(bipy)(dppb)]PF6 (2) that are analogs to an antitumor agent recently described, [Ru(SpymMe2)(bipy)(dppb)]PF6 (3), where ...
Synthesis, characterization and biological activity of platinum(II) complexes with a tetrapyrazole ligand
(PERGAMON-ELSEVIER SCIENCE LTD, 2015)
In the search of an effective chemotherapy for the treatment of cancer, in this work we describe the synthesis, characterization and biological activity of two new platinum complexes. The general formula is [Pt-2(L)(X)(4)], ...