Now showing items 1-10 of 344
Non-myogenic tumors display altered expression of dystrophin (DMD) and a high frequency of genetic alterations
(Impact Journals LLC, 2017-01)
DMD gene mutations have been associated with the development of Dystrophinopathies. Interestingly, it has been recently reported that DMD is involved in the development and progression of myogenic tumors, assigning DMD a ...
Human adipose tissue derived pericytes increase life span in Utrn tm1Ked Dmd mdx /J Mice
Duchenne muscular dystrophy (DMD) is still an untreatable lethal X-linked disorder, which affects 1 in 3500 male births. It is caused by the absence of muscle dystrophin due to mutations in the dystrophin gene. The potential ...
The value of dog for knowledge of human Duchenne muscular dystrophy: New findings in pathogenesis and therapeutic advances
Duchenne muscular dystrophy (DMD) is the most devastating form of inherited muscular dystrophy in men. The loss of dystrophin causes progressive weakness and degeneration of skeletal and cardiac muscle leading to the ...
Autonomic modulation in duchenne muscular dystrophy during a computer task: A prospective control trial
Introduction: Duchenne Muscular Dystrophy (DMD) is characterized by progressive muscle weakness that can lead to disability. Owing to functional difficulties faced by individuals with DMD, the use of assistive technology ...
Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis
Background: Duchenne muscular dystrophy (DMD) is characterized by the absence of the cytoskeletal protein dystrophin, muscle wasting, increased transforming growth factor type beta (TGF-β) signaling, and fibrosis. At the ...
Heart Rate Variability and Cardiopulmonary Dysfunction in Patients with Duchenne Muscular Dystrophy: A Systematic Review
Duchenne muscular dystrophy (DMD) is a genetic recessive disorder with progressive muscle weakness. Despite the general muscle wasting, degeneration and necrosis of cardiomyocytes have been the main causes of morbidity and ...
Family-based genome-wide association study in Patagonia confirms the association of the DMD locus and cleft lip and palate
(Wiley Blackwell Publishing, Inc, 2015-10)
The etiology of cleft lip with or without cleft palate (CL±P) is complex and heterogeneous, and multiple genetic and environmental factors are involved. Some candidate genes reported to be associated with oral clefts are ...
Análise histoquímica e morfométrica de fibras musculares estriadas esqueléticas em pacientes com distrofia muscular de Duchenne (DMD)
(Universidade Federal de Pernambuco, 2014)