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Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco
(Cambridge University Press, 2013-03)
The discrete typing units (DTUs) of Trypanosoma cruzi that infect domestic dogs and cats have rarely been studied. With this purpose we conducted a cross-sectional xenodiagnostic survey of dog and cat populations residing ...
Geographic variation of Trypanosoma cruzi Discrete Typing Units from the main vector Triatoma infestans at different scales
(Elsevier, 2014-08-01)
tWe assessed the diversity and distribution of Trypanosoma cruzi discrete typing units (DTU) in Triatomainfestans populations and its association with local vector-borne transmission levels at various geographicscales. At ...
Differential distribution of genes encoding the virulence factor trans-sialidase along Trypanosoma cruzi discrete typing units
(Public Library Of Science, 2013-03)
Trypanosoma cruzi the agent of Chagas disease is a monophyletic but heterogeneous group conformed by several Discrete Typing Units (DTUs) named TcI to TcVI characterized by genetic markers. The trans-sialidase (TS) is a ...
Deep sequencing to detect diversity of Trypanosoma cruzi infection in patients co-infected with HIV and Chagas disease
(Oxford University Press, 2021)
Chagas disease, caused by Trypanosoma cruzi, can reactivate and cause severe acute disease in immunocompromised patients such as those infected with HIV. We conducted amplicon deep sequencing of a 327-base pair fragment ...
Identification of Trypanosoma cruzi Discrete Typing Units (DTUs) in Latin-American migrants in Barcelona (Spain)
(Elsevier Ireland, 2017-04)
Trypanosoma cruzi, the causative agent of Chagas disease, is divided into six Discrete Typing Units (DTUs): TcI–TcVI. We aimed to identify T. cruzi DTUs in Latin-American migrants in the Barcelona area (Spain) and to assess ...
Direct molecular identification of Trypanosoma cruzi Discrete Typing Units in domestic and peridomestic Triatoma infestans and Triatoma sordida from the Argentine Chaco
(Cambridge University Press, 2012-10)
We assessed the distribution of Trypanosoma cruzi Discrete Typing Units (DTUs) in domestic and peridomestic Triatoma infestans and Triatoma sordida specimens collected in a well-defined rural area in Pampa del Indio, ...
Differential tissue distribution of discrete typing units after drug combination therapy in experimental Trypanosoma cruzi mixed infection
(Cambridge University Press, 2021-11)
The aim of the present work was to evaluate the distribution of the different clones of the parasite prevailing after treatment with benznidazole (BZ) and clomipramine (CLO), in mice infected with Trypanosoma cruzi, Casibla ...
Molecular diagnosis of Trypanosoma cruzi
(Elsevier Science, 2018-08)
Chagas disease, caused by the kinetoplastid protozoan Trypanosoma cruzi, affects millions of people, most of them neglected populations. The different phases of the disease, the transmission mode and the high genetic ...