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Copper as an essential nutrient
(American Society for Nutrition, 1996)
Animal and human studies have shown that copper is involved in the function of several enzymes. Studies have also shown that copper is required for infant growth, host defense mechanisms, bone strength, red and white cell ...
How reliable and robust are current biomarkers for copper status?
Cu is an essential nutrient for man, but can be toxic if intakes are too high. In sensitive populations, marginal over- or under-exposure can have detrimental effects. Malnourished children, the elderly, and pregnant or ...
Gene chip analyses reveal differential genetic responses to iron deficiency in rat duodenum and jejunum
(Sociedad de Biología de Chile, 2006)
Phagocytosis and immunoglobulin levels in hypocupremic infants
Nineteen hypocupremic marasmic infants 5-14 months of age with a normal wt/1gth ratio, were immunologically evaluated during their rehabilitation. The infants were studied 2-3 months after admission to a Closed Nutritional ...
Erythrocyte CuZn superoxide dismutase activity is decreased in iron-deficiency anemia
Iron and copper are essential microminerals that are intimately related. The present study was performed to determine the effect of iron-deficiency anemia (IDA) and treatment with iron on laboratory indicators of copper ...
Assessing chaperone for Zn, Cu-superoxide dismutase as an indicator of copper deficiency in malnourished children
It is not clear how frequent is copper deficiency in humans. Current copper markers are not sensitive enough to detect early copper deficiency and new markers are needed. CCS is a candidate to become a copper ...
Copper deficiency in Creole goat kids
(EDP Sciences, 2002-09-25)
Serum copper determination is important to confirm hypocupremia. Twenty healthy kids constituted the Control Group, and sixteen kids with symptoms of copper deficiency, the Problem Group. Animals from the Problem Group ...
Present situation of biomarkers for copper status 1-3
(The American Society for Nutrition, 2008)
Serum or plasma copper and ceruloplasmin concentrations are the most widely used laboratory indicators to evaluate copper status. Both indicators are decreased in moderate or severe copper deficiency. The activity of ...
Expression of copper-related genes in response to copper load
(AMER SOC CLINICAL NUTRITION, 2008-09-01)
Copper is an essential micronutrient for all biological systems. Multiple proteins require one or more atoms of copper for proper structure and function, but excess of copper is toxic. To prevent the consequences of copper ...
COPPER DEFICIENCY ALTERS CELL BIOENERGETICS AND INDUCES MITOCHONDRIAL FUSION THROUGH UP-REGULATION OF MFN2 AND OPA1 IN ERYTHROPOIETIC CELLS
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013)