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Conformational cooling and conformation selective aggregation in dimethyl sulfite isolated in solid rare gases
(Elsevier Science, 2006-08)
Dimethyl sulfite has three conformers of low energy, GG, GT and GG0 , which have significant populations in the gas phase at room temperature. According to theoretical predictions, the GT and GG0 conformers are higher in ...
Implementing complementary approaches to shape the mechanism of α-synuclein oligomerization as a model of amyloid aggregation
(Molecular Diversity Preservation International, 2022)
NF kappa B is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation
(Amer Soc Cell Biology, 2016)
During cell life, proteins often misfold, depending on particular mutations or environmental changes, which may lead to protein aggregates that are toxic for the cell. Such protein aggregates are the root cause of numerous ...
Supramolecular aggregates of oligosaccharides with co-solvents in ternary systems for the solubilizing approach of triamcinolone
(Elsevier, 2016-10)
A second compound is generally associated with oligosaccharides as a strategy to maximize the solubilizing effect for nonpolar compounds. This study elucidated the role and the mechanism whereby liquid compounds interact ...
Luminescent imaging of insulin amyloid aggregation using a sensitive ruthenium-based probe in the red region
(2021-11-01)
A sensitive and selective strategy to identify insulin fibrils remains a challenge for researchers in amyloid protein research. Thus, it is critical to detect, in vitro, the species generated during amyloid aggregation, ...
Binding of the substrate UDPglucuronic acid induces conformational changes in the xanthan gum glucuronosyltransferase
(Oxford University Press, 2016-06)
GumK is a membrane-associated glucuronosyltransferase of Xanthomonas campestris that is involved in xanthan gum biosynthesis. GumK belongs to the inverting GT-B superfamily and catalyzes the transfer of a glucuronic acid ...
Flexibility of the triblock copolymers modulating their penetration and expulsion mechanism in Langmuir monolayers of dihexadecyl phosphoric acid
(Elsevier Science BvAmsterdamHolanda, 2001)
Estudio de la agregación de la proteína beta amiloide a través de técnicas de microscopía de fuerza atómica empleando el péptido disruptor LPFFD y nanopartículas de oro
(Universidad de Chile, 2008)
La proteína beta amiloide (Aβ), involucrada en la enfermedad de Alzheimer, cambia su conformación en condiciones patológicas formando agregados tóxicos (AT) que tienen un efecto neurodegenerativo. La estructura molecular ...