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Increased Gi protein signaling potentiates the negative chronotropic effect of adenosine in the SHR right atrium
(Springer, 2018)
Hypertension is a risk factor for cardiovascular diseases, which have been associated with dysfunction of sympathetic and purinergic neurotransmission. Therefore, herein, we evaluated whether modifications of adenosine ...
Negative inotropic and chronotropic effects on the guinea pig atrium of extracts obtained from Averrhoa carambola L. leaves
(Associação Brasileira de Divulgação Científica, 2016)
Chronotropic response to (+/-)-CGP12177 in right atria of stressed rats
(Natl Research Council CanadaOttawaCanadá, 2001)
Role of nitric oxide/cyclic GMP and cyclic AMP in β3 adrenoceptor-chronotropic response
(Academic Press Ltd - Elsevier Science Ltd, 2006-04)
In this study we determine different signaling pathways involved in â3 adrenoceptor- (â3-AR) dependent frequency stimulation in isolated rodent atria. Promiscuous coupling between different G-proteins and â3-AR could ...
Metabolic and functional consequences of cytosolic 5′-nucleotidase-IA overexpression in neonatal rat cardiomyocytes
(American Physiological Society, 2003-09)
Adenosine exerts a spectrum of energy-preserving actions on the heart negative chronotropic effects. The pathways leading to adenosine formation have remained controversial. In particular, although cytosolic 5′-nucleotidases ...
RELATIONSHIP AMONG SENSITIVITY TO ADRENALINE, PLASMA-CORTICOSTERONE LEVEL, AND ESTROUS-CYCLE IN RATS
(Natl Research Council CanadaOttawaCanadá, 1995)