Immunotherapy is currently regarded as the most promising treatment to fight against cancer. This is particularly true in the treatment of chronic lymphocytic leukemia, an indolent neoplastic disease of B-lymphocytes which ...

Background The malignant B cells in chronic lymphocytic leukemia receive signals from the bone marrow and lymph node microenvironments which regulate their survival and proliferation. Characterization of these signals and ...

Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. Due to its catalytic activity, LPL is involved in metabolic pathways exploited by various solid and hematologic malignancies to provide an extra energy ...

Histological images analysis is an important procedure to diagnose different types of cancer. One of them is the chronic lymphocytic leukemia (CLL), which can be identified by applying image segmentation techniques. This ...

The old paradigm that establishes that neutrophils are just short half-life cells committed to kill bacteria in situ at early stages of infection is changing. Nowadays, there are plenty of reports that focus on neutrophils ...

Indole-3-acetic acid (IAA), when oxidized by horseradish peroxidase (HRP), is transformed into cytotoxic molecules capable of inducing cell injury. The aim of this study was to test if, by targeting hematopoietic tumors ...