Now showing items 1-10 of 315
A mathematical model for chemoimmunotherapy of chronic lymphocytic leukemia
Immunotherapy is currently regarded as the most promising treatment to fight against cancer. This is particularly true in the treatment of chronic lymphocytic leukemia, an indolent neoplastic disease of B-lymphocytes which ...
The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets
(FERRATA STORTI FOUNDATIONPAVIA, 2012)
Background The malignant B cells in chronic lymphocytic leukemia receive signals from the bone marrow and lymph node microenvironments which regulate their survival and proliferation. Characterization of these signals and ...
Diagnosis And Treatment Of Chronic Lymphocytic Leukemia: Recommendations From The Brazilian Group Of Chronic Lymphocytic Leukemia
(Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2016)
Lipoprotein lipase expression in chronic lymphocytic leukemia: new insights into leukemic progression
Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. Due to its catalytic activity, LPL is involved in metabolic pathways exploited by various solid and hematologic malignancies to provide an extra energy ...
Immunological effects of interferon-alpha on chronic myelogenous leukemia
(Taylor & Francis LtdAbingdonInglaterra, 2003)
Using wavelet sub-band and fuzzy 2-partition entropy to segment chronic lymphocytic leukemia images
Histological images analysis is an important procedure to diagnose different types of cancer. One of them is the chronic lymphocytic leukemia (CLL), which can be identified by applying image segmentation techniques. This ...
Neglected players: Tumor associated neutrophils involvement in chronic lymphocytic leukemia progression
(Impact Journals, 2019-03)
The old paradigm that establishes that neutrophils are just short half-life cells committed to kill bacteria in situ at early stages of infection is changing. Nowadays, there are plenty of reports that focus on neutrophils ...
Antibody-targeted horseradish peroxidase associated with indole-3-acetic acid induces apoptosis in vitro in hematological malignancies
(Pergamon-Elsevier B.V. Ltd, 2011-05-01)
Indole-3-acetic acid (IAA), when oxidized by horseradish peroxidase (HRP), is transformed into cytotoxic molecules capable of inducing cell injury. The aim of this study was to test if, by targeting hematopoietic tumors ...