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Amphibian oocytes respond to heat shock after the induction of meiotic maturation by hormones
Exposure of Xenopus laevis oocytes to temperatures above 31° causes a drastic decrease in protein synthesis and a relative increase of a heat shock protein (HSP) of approximate molecular weight of 68,000. A significant ...
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2
(Nature Publishing Group, 2007)
Regulation of ribosomal RNA genes is a fundamental process that supports the growth of cells and is tightly coupled with cell differentiation. Although rRNA transcriptional control by RNA polymerase I (Pol I) and associated ...
Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2
During cell division, cessation of transcription is coupled with mitotic chromosome condensation. A fundamental biological question is how gene expression patterns are retained during mitosis to ensure the phenotype of ...
Changes in nuclear distribution of large tumor antigen correlate with the proliferative activity of simian virus 40-transformed cells
A correlation between intranuclear distribution of large tumor antigen (T-ag) and proliferative activity in Simian virus 40 (SV40)-transformed cells has been established. Nuclear T-ag was cytochemically detected by the ...