Now showing items 1-10 of 573
Cytogenetic evaluation of 20 primary breast carcinomas
Chromosome analysis was performed on samples from 20 Brazilian patients with breast cancer. All the samples were from untreated patients who presented the clinical symptoms for months or years before surgical intervention. ...
Human chromosome aberrations induced in vitro by Paracoccidioides brasiliensis glycoproteic component (GP 43)
The in vitro cytogenetic effects of the 43-kDa molecular mass exocellular glycoproteic component (GP 43) from Paracoccidioides brasiliensis were studied in cultures from human lymphocytes. The sample included 10 healthy, ...
Different responses to doxorubicin-induced chromosome aberrations in Brazilian deer species
The tendency toward chromosome fragility is one of the theories that may explain chromosome variation in brocket deer species (genus Mazama). We tested doxorubicin as an inducer of chromosome aberrations in lymphocytes of ...
Isochromosome Y in an infertile heifer
Identifying Mazama gouazoubira (Artiodactyla; Cervidae) chromosomes involved in rearrangements induced by doxorubicin
The process of karyotype evolution in Cervidae from a common ancestor (2n = 70, FN = 70) has been marked by complex chromosomal rearrangements. This ancestral karyotype has been retained by the current species Mazama ...
Chromosome aberrations as a predictor of clinical outcome for smoking associated lung cancer
(Elsevier B.V., 2000-09-29)
The ability to identify individuals at greatest risk of developing lung cancer can significantly enhance the efficacy of intervention modalities. One strategy for identifying these individuals is through biomarkers that ...
Multiple cytogenetic clones in a basal cell carcinoma
Chromosome analysis of short-term culture of a basal cell carcinoma showed five clonal chromosome abnormalities, t(9;14)(q12 or q13;p11), del(1)(q23 or q25), trisomy 5, trisomy 7, and monosomy X. In addition, several ...