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A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
(2016)
Chinese hamster ovary (CHO) cells dominate biotherapeutic protein production and are widely used in mammalian cell line engineering research. To elucidate metabolic bottlenecks in protein production and to guide cell ...
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
(2016)
Chinese hamster ovary (CHO) cells dominate biotherapeutic protein production and are widely used in mammalian cell line engineering research. To elucidate metabolic bottlenecks in protein production and to guide cell ...
Development of a new promoter to avoid the silencing of genes in the production of recombinant antibodies in chinese hamster ovary cells
(BioMed Central Ltd., 2019)
Background: The production of recombinant proteins in mammalian cell lines is one of the most important areas in biopharmaceutical industry. Viral transcriptional promoters are widely used to express recombinant proteins ...
STREPTOZOTOCIN-INDUCED TOXICITY IN CHO-9 AND V79 CELLS
(Wiley-lissNew York, 1995)
STREPTOZOTOCIN-INDUCED CHROMOSOMAL-ABERRATIONS, SCES AND MUTATIONS IN CHO-9 PARENTAL CELLS AND IN EM-C-11 MUTANT-CELL LINE
(Elsevier Science BvAmsterdamHolanda, 1995)
Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase
(HINDAWI PUBLISHING CORPORATIONNEW YORK, 2012)
Impaired activity of the lysosomal enzyme glucocerebrosidase (GCR) results in the inherited metabolic disorder known as Gaucher disease. Current treatment consists of enzyme replacement therapy by administration of exogenous ...