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Probing the pore size of the hemocyanin channel
(1982)
We have studied single-channel conductance for different monovalent cations and streaming potentials caused by osmotic gradients of non-electrolytes in hemocyanin-treated membranes. We have found that the smaller ion, which ...
Counting channels: a tutorial guide on ion channel fluctuation analysis
(American Physiological Society, 2002)
Ion channels open and close in a stochastic fashion, following the laws of
probability. However, distinct from tossing a coin or a die, the probability of
finding the channel closed or open is not a fixed number but can ...
Differential effects of beta 1 and beta 2 subunits on BK channel activity
(ROCKEFELLER UNIV PRESS, 2005-04)
High conductance, calcium- and voltage-activated potassium (BK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory (beta) ...
Voltage-controlled gating in a large conductance Ca2+-sensitive K(+)channel (hslo)
(NATL ACAD SCIENCES, 1997-05-13)
Large conductance calcium- and voltage-sensitive K+ (MaxiK) channels share properties of voltage- and ligand-gated ion channels. In voltage-gated channels, membrane depolarization promotes the displacement of charged ...
Molecular coupling between voltage sensor and pore opening in the Arabidopsis inward rectifier K+ channel KAT1
(ROCKEFELLER UNIV PRESS, 2003-10)
Animal and plant voltage-gated ion channels share a common architecture. They are made up of four subunits and the positive charges on helical S4 segments of the protein in animal K+ channels are the main voltage-sensing ...
Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1998-12-04)
We investigated the role of individual charged residues of the S4 region of a MaxiK channel (hSlo) in channel gating, We measured macroscopic currents induced by wild type (WT) and point mutants of hSlo in inside-out ...
A BK (Slo1) channel journey from molecule to physiology
(Taylor and Francis Inc., 2013)
Calcium and voltage-activated potassium (BK) channels are key actors in cell physiology, both in neuronal and non-neuronal cells and tissues. Through negative feedback between intracellular Ca2+ and membrane voltage, BK ...
Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans
(Elsevier, 2013)
The transient receptor potential melastatin (TRPM) protein family is an extensive group of ion channels
expressed in several types of mammalian cells. Many studies have shown that these channels are crucial
for performing ...
Structure and function of channels and channelogs as studied by computational chemistry
(Springer-Verlag, 1991)
Efficient Channel Allocation Algorithm with Partial CSI for the PB/MC-CDMA System
(Springer, 2015)
Abstract An efficient channel allocation algorithm is proposed for the Partial Block MCCDMA
system. Partial channel state information is used for determining the signal-to-noise
ratio of all frequency-block-bands. The ...