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QSAR study for carcinogenicity in a large set of organic compounds
(Bentham Science Publishers, 2012-11)
In our continuing efforts to find out acceptable Absorption, Distribution, Metabolization, Elimination and Toxicity (ADMET) properties of organic compounds, we establish linear QSAR models for the carcinogenic potential ...
Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions
(Pergamon-Elsevier Science Ltd, 2009-01)
Several nitrofurans and nitroimidazoles have been widely used in veterinary medicine. Some of these compounds are breast carcinogens in rodents and their mechanism of action is hypothesized to be related to reactive ...
Determination of 2-methylimidazole and 4-methylimidazole in caramel colors by capillary electrophoresis
(2013-03-06)
The use of chemical preservative compounds is common in the food products industry. Caramel color is the most usual additive used in beverages, desserts, and breads worldwide. During its fabrication process, 2- and ...
Determination of 2-methylimidazole and 4-methylimidazole in caramel colors by capillary electrophoresis
(2013-03-06)
The use of chemical preservative compounds is common in the food products industry. Caramel color is the most usual additive used in beverages, desserts, and breads worldwide. During its fabrication process, 2- and ...
Prediction of non-genotoxic carcinogenicity based on genetic profiles of short term exposure assays
(Korean Society of Toxicology, 2016-06)
Non-genotoxic carcinogens are substances that induce tumorigenesis by non-mutagenic mechanisms and long term rodent bioassays are required to identify them. Recent studies have shown that transcription profiling can be ...