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Synthesis, Secondary Structure, and Anion Binding of Acyclic Carbohydrate-Derived Oligo(amide-triazole)s
(Wiley VCH Verlag, 2018-12)
A family of linear, carbohydrate-derived oligo(amide-triazole)s has been designed and synthesized. These molecules possess a regular distribution of triazole rings (from one to four) linking the carbohydrate units to give ...
Evidence for Conformational Mechanism on the Binding of TgMIC4 with beta-Galactose-Containing Carbohydrate Ligand
(Amer Chemical Soc, 2015-11-10)
A deeper understanding of the role of sialic/desialylated groups during TgMIC4-glycoproteins interactions has importance to better clarify the odd process of host cell invasion by members of the apicomplexan phylum. Within ...
An efficient use of X-ray information, homology modeling, molecular dynamics and knowledge-based docking techniques to predict protein-monosaccharide complexes
(Oxford University Press, 2018-11)
Unraveling the structure of lectin-carbohydrate complexes is vital for understanding key biological recognition processes and development of glycomimetic drugs. Molecular Docking application to predict them is challenging ...
First synthesis of (-)-neplanocin C
(Pergamon-Elsevier Science Ltd, 2000-06)
(-)-Neplanocin C (4), a minor component of the neplanocin family of antibiotics and a lead drug for the design of several conformationally constrained nucleosides analogues, was enantioselectively synthesized starting from ...
Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties
(2016)
Calreticulin (CRT) is a multifaceted protein, initially discovered as an endoplasmic reticulum (ER) chaperone protein, that is essential in calcium metabolism. Various implications in cancer, early development and immunology ...
Molecular Characterization Of A Family 5 Glycoside Hydrolase Suggests An Induced-fit Enzymatic Mechanism
(NATURE PUBLISHING GROUPLONDON, 2016)
Molecular Characterization Of A Family 5 Glycoside Hydrolase Suggests An Induced-fit Enzymatic Mechanism
(Nature Publishing GroupLondon, 2016)
Triple helix conformation of botryosphaeran, a (1 -> 3;1 -> 6)-beta-D-glucan produced by Botryosphaeria rhodina MAMB-05
(Elsevier B.V., 2008-11-21)
Botryosphaeran, a (1 -> 3;1 -> 6)-beta-D-glucan produced by Botryosphaeria rhodina MAMB-05, was found to be present in a triple helix conformation from helix-coil transition studies using Congo Red. The triple helix ...