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An evidence-based approach to identify aging-related genes in Caenorhabditis elegans
(2015)
Abstract
Background
Extensive studies have been carried out on Caenorhabditis elegans as a model organism to elucidate mechanisms of aging and the effects of perturbing known ...
Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging : Role of redox homeostasis
(2019-02)
The insulin-IGF-1/DAF-2 pathway has a central role in the determination of aging and longevity in Caenorhabditis elegans and other organisms. In this paper, we measured neuronal insulin secretion (using INS-22::Venus) ...
Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans
(BMC, 2019)
Background: Chagas disease (CD) is a tropical parasitic disease. Although the number of people infected is very
high, the only drugs available to treat CD, nifurtimox (Nfx) and benznidazole, are highly toxic, particularly ...
Caenorhabditis elegans infrared-based motility assay identified new hits for nematicide drug development
(MDPI, 2019)
Nematode parasites have a profound impact on humankind, infecting nearly one-quarter of the world’s population, as well as livestock. There is a pressing need for discovering nematicides due to the spread of resistance to ...
Small-worldness favours network inference in synthetic neural networks
(Nature Research, 2020)
A main goal in the analysis of a complex system is to infer its underlying network structure from timeseries observations of its behaviour. The inference process is often done by using bi-variate similarity measures, such ...
A liaR deletion restores susceptibility to daptomycin and antimicrobial peptides in multidrug-resistant Enterococcus faecalis
(The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America, 2015)
Daptomycin is a lipopeptide antibiotic that is used clinically against many gram-positive bacterial pathogens and is considered a key frontline bactericidal antibiotic to treat multidrug-resistant enterococci. Emergence ...
A liaR deletion restores susceptibility to daptomycin and antimicrobial peptides in multidrug-resistant Enterococcus faecalis
(The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America, 2015)
Daptomycin is a lipopeptide antibiotic that is used clinically against many gram-positive bacterial pathogens and is considered a key frontline bactericidal antibiotic to treat multidrug-resistant enterococci. Emergence ...