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CXCL12 estimula fibroblastos pulmonares a produzir CCL3, CXCL2, LTB4 e LTC4 via p38, MEK1/2, PI-3K e JNK
(Universidade Estadual Paulista (Unesp), 2014)
CXCL12 estimula fibroblastos pulmonares a produzir CCL3, CXCL2, LTB4 e LTC4 via p38, MEK1/2, PI-3K e JNK
(Universidade Estadual Paulista (UNESP), 2014)
CXCL5, CXCL8, and CXCL10 regulation by bacteria and mechanical forces in periodontium
(2021-03-01)
Objective: The aim of the present study was to evaluate the expressions of CXCL5, CXCL8, and CXCL10 in periodontal cells and tissues in response to microbial signals and/or biomechanical forces. Methods: Human gingival ...
CXCL12 estimula fibroblastos pulmonares a produzir CCL3, CXCL2, LTB4 e LTC4 via p38, MEK1/2, PI-3K e JNK
(Universidade Estadual Paulista (Unesp), 2013-08-05)
C-X-X motif ligand 12 (CXCL12) and its specific receptor Chemokine receptor 4 (CXCR4) play a critical role in airway inflammation. However, the effects of CXCL12/CXCR4 axis on pulmonary fibroblast activation are unknown. ...
Estudo da secreção de CXCL12 por astrócitos e células-tronco mesenquimais
(Universidade Federal de São Paulo (UNIFESP), 2015-06-24)
O CXCL12 é uma quimiocina presente na maioria dos tecidos de mamíferos. Possui dois receptores conhecidos, o CXCR4 e o CXCR7, porém a maior parte de suas funções está relacionada à ativação do CXCR4. Na neurobiologia, sua ...
Protein Kinase C Epsilon Cooperates with PTEN Loss for Prostate Tumorigenesis through the CXCL13-CXCR5 Pathway
(Elsevier Science, 2017-04)
PKCε, an oncogenic member of the PKC family, is aberrantly overexpressed in epithelial cancers. To date, little is known about functional interactions of PKCε with other genetic alterations, as well as the effectors ...
Potential Role of CXCL10 in Monitoring Response to Treatment in Leprosy Patients
(Frontiers Media, 2022)
Induction of TNF-alfa and CXCL-2 mRNAs in different organs of mice infected with pathogenic Leptospira
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTDLONDON, 2013-08-02)
The role of innate immune response in protection against leptospirosis is poorly understood. We examined the expression of the chemokine CXCL2/MIP-2 and the cytokine TNF-alpha. in experimental resistant and susceptible ...