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Expanding cyclitol structural diversity by biocatalysis and metalocatalysis. A click chemistry approach
(SPRINGER, 2011)
The palladium catalyzed cross-coupling reaction of phenyltrifluoroborate with a chemoenzymatically derived bromoazidoconduritol, combined with 1,3-dipolar cycloaddition, with a variety of alkynes is described. Fourteen new ...
Synthesis of 1,2,3-triazolylpyranosides through click chemistry reaction
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
We have developed an efficient method for the synthesis of functionalized C-glycosyl 1,2,3-triazoles through a Cu(1)-promoted azide-alkyne 1,3-dipolar cycloaddition between a TMS-protected C-alkynyl-glycoside and organic ...
Application of copper(I)-catalysed azide/alkyne cycloaddition (CuAAC) `click chemistry` in carbohydrate drug and neoglycopolymer synthesis
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
A peptide-based coating toolbox to enable click chemistry on polymers, metals, and silicon through sortagging
(Wiley-Blackwell, 2021-02-04)
A versatile peptide-based toolbox for surface functionalization was established by a combination of a universal material binding peptide (LCI-anchor peptide) and sortase-mediated bioconjugation (sortagging). This toolbox ...
Preparation of bifunctional mesoporous silica nanoparticles by orthogonal click reactions and their application in cooperative catalysis
(Wiley-VCH VerlagWeinheim, 2012-12)
The synthesis of bifunctional mesoporous silica nanoparticles is described. Two chemically orthogonal functionalities are incorporated into mesoporous silica by co-condensation of tetraethoxysilane with two orthogonally ...
Palladium Nanoparticles Embedded in a Layer-by-Layer Nanoreactor Built with Poly(Acrylic Acid) Using "electro-Click Chemistry"
(American Chemical Society, 2016-07)
Palladium nanoparticles (Pd NPs) were formed by electrochemical reduction of Pd(NH3)43+ ions entrapped by ion exchange in poly(acrylic acid) (PAA) multilayer films grown by the Sharpless "click reaction." The alkyne (PAAalk) ...
Simple thiol-ene click chemistry modification of SBA-15 silica pores with carboxylic acids
(Academic Press Inc Elsevier Science, 2015-07)
A straightforward approach for anchoring tailored carboxylic groups in mesoporous SiO2 colloidal materials is presented. The thiol-ene photochemical reaction between vinyltrimethoxysilane precursors and various thiocarboxylic ...
Increase of leishmanicidal and tubercular activities using steroids linked to aminoquinoline
(2012)
Background: Aminoquinoline/steroid conjugates were synthesized based on the fact that steroid transporters have been shown to accept and carry a variety of drugs. So, in continuing our research of antileishmanial and ...
Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
This work describes the synthesis of a series of sialylmimetic neoglycoconjugates represented by 1,4-disubstituted 1,2,3-triazole-sialic acid derivatives containing galactose modified at either C-1 or C-6 positions, glucose ...
Chemoenzymatic Synthesis of Triazololactams Structurally Related to Pancratistatin
(Wiley VCH Verlag, 2017-07-17)
Four tricyclic lactams that structurally resemble alkaloids with the pancratistatin skeleton were synthetized from bromobenzene by a chemoenzymatic strategy. The sequence involved enzymatic dihydroxylation, efficient ...