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Using telomeric chromosomal aberrations to evaluate clastogen-induced genomic instability in mammalian cells
(Springer, 2020-12)
Telomeres, the specialized nucleoproteic complexes localized at the physical ends of linear eukaryotic chromosomes, play a fundamental role in maintaining chromosomal stability and integrity, being one of the leading ...
Structural chromosome instability: Types, origins, consequences, and therapeutic opportunities
(Molecular Diversity Preservation International, 2021-06)
Chromosomal instability (CIN) refers to an increased rate of acquisition of numerical and structural changes in chromosomes and is considered an enabling characteristic of tumors. Given its role as a facilitator of genomic ...
Interstitial telomeric sequences in vertebrate chromosomes: Origin, function, instability and evolution
(Elsevier Science, 2017-07)
By definition, telomeric sequences are located at the very ends or terminal regions of chromosomes. However, several vertebrate species show blocks of (TTAGGG)n repeats present in non-terminal regions of chromosomes, the ...
Ring chromosome instability evaluation in six patients with autosomal rings
(FUNPEC-EDITORA, 2010)
Ring chromosomes are often associated with abnormal phenotypes due to loss of genomic material and also because of ring instability at mitosis after sister chromatid exchange events. We investigated ring chromosome instability ...
Ring chromosome instability evaluation in six patients with autosomal rings
(Funpec-editora, 2010-01-01)
Ring chromosomes are often associated with abnormal phenotypes due to loss of genomic material and also because of ring instability at mitosis after sister chromatid exchange events. We investigated ring chromosome instability ...
Chromosome Instability in Carcinomas
(Sociedad Chilena de Anatomía, 2006)
Caracterização de pontos de quebras de DNA e rearranjos cromossômicos no gênero Harttia (Siluriformes: Loricariidae)
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEvCâmpus São Carlos, 2022-04-04)
Harttia genus comprises a fish group widely distributed in hydrographic basins of South
America. In the cytogenetic point of view, present large karyotypic variation, including
an extensive variation in position of ...
Cytogenetic analysis of B chromosomes in one population of the fish Moenkhausia sanctaefilomenae (Steindachner, 1907) (Teleostei, Characiformes)
(Zoological Inst, 2012-01-01)
The aim of this study was to characterize cytogenetically one population of the fish Moenkhausia sanctaefilomenae (Steindachner, 1907), with emphasis on the analysis of B chromosomes. The nucleolar activity in the B ...
Cytogenetic analysis of B chromosomes in one population of the fish Moenkhausia sanctaefilomenae (Steindachner, 1907) (Teleostei, Characiformes)
(Zoological Inst, 2012-01-01)
The aim of this study was to characterize cytogenetically one population of the fish Moenkhausia sanctaefilomenae (Steindachner, 1907), with emphasis on the analysis of B chromosomes. The nucleolar activity in the B ...
Cytogenetic analysis of B chromosomes in one population of the fish Moenkhausia sanctaefilomenae (Steindachner, 1907) (Teleostei, Characiformes)
(2012-01-01)
The aim of this study was to characterize cytogenetically one population of the fish Moenkhausia sanctaefilomenae (Steindachner, 1907), with emphasis on the analysis of B chromosomes. The nucleolar activity in the B ...