Buscar
Mostrando ítems 1-10 de 346
Short-range regulatory chromatin loops in plants
(Wiley Blackwell Publishing, Inc, 2020-04)
In all eukaryotic organisms, gene expression correlates with the condensation state of the chromatin. Highly packed genome regions, known as heterochromatins, are associated with repressed loci, whereas euchromatic regions ...
Interplay among ATP-Dependent Chromatin Remodelers Determines Chromatin Organisation in Yeast
(Multidisciplinary Digital Publishing Institute, 2020-07)
Cellular DNA is packaged into chromatin, which is composed of regularly-spaced nucleosomes with occasional gaps corresponding to active regulatory elements, such as promoters and enhancers, called nucleosome-depleted regions ...
Meta-analysis of Chromatin Programming by Steroid Receptors
(Elsevier, 2019-09)
Transcription factors (TFs) must access chromatin to bind to their response elements and regulate gene expression. A widely accepted model proposes that only a special subset of TFs, pioneer factors, can associate with ...
Chromatin dynamics during interphase explored by single-particle tracking
(Springer, 2008-05)
Our view of the structure and function of the interphase nucleus has changed drastically in recent years. It is now widely accepted that the nucleus is a well organized and highly compartmentalized organelle and that this ...
Editorial: Plant Genome-Epigenome Integrity Under Environmental Stress
(Frontiers Media, 2020-08)
Plants, due to their sessile life style, need to cope with different environmental stresses to allow proper growth and development. DNA, in association with histones, is packaged into chromatin. Several changes in chromatin ...
Chromatin, DNA structure and alternative splicing
(Elsevier Science, 2015-06)
Coupling of transcription and alternative splicing via regulation of the transcriptional elongation rate is a well-studied phenomenon. Template features that act as roadblocks for the progression of RNA polymerase II ...
A chromatin code for alternative splicing involving a putative association between CTCF and HP1aα proteins
(BioMed Central, 2015-12-02)
Background: Alternative splicing is primarily controlled by the activity of splicing factors and by the elongation of the RNA polymerase II (RNAPII). Recent experiments have suggested a new complex network of splicing ...
Crosstalk between DNA methylation chromatin structure
(Elsevier, 2016)
Regulation of gene expression is the result of a functional crosstalk between multiple epigenetic pathways. DNA methylation is an epigenetic mark that is typically related to gene silencing. Changes in DNA methylation are ...
Global histone protein surface accessibility in yeast indicates a uniformly loosely packed genome with canonical nucleosomes
(BioMed Central, 2021-12-11)
Background: The vast majority of methods available to characterize genome-wide chromatin structure exploit differences in DNA accessibility to nucleases or chemical crosslinking. We developed a novel method to gauge ...
Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination
(Cold Spring Harbor Laboratory Press, 2019-03)
Most yeast genes have a nucleosome-depleted region (NDR) at the promoter and an array of regularly spaced nucleosomes phased relative to the transcription start site. We have examined the interplay between RSC (a conserved ...