Search
Now showing items 1-10 of 15
Enzyme-catalyzed preparation of chenodeoxycholic esters by an immobilized heterologous Rhizopus oryzae lipase
(Elsevier Science, 2015-08)
A lipase-catalyzed preparation of ethyl and stearyl esters of chenodeoxycholic acid is described. Stearyl chenodeoxycholate is a new product and both bile acid esters were prepared through an enzymatic approach for the ...
Cerebrotendinous Xanthomatosis Revealed in Drug-Resistant Epilepsy Diagnostic Workup
(Lippincott Williams, 2012-04)
Cerebrotendinous xanthomatosis (CTX) is a treatable disorder of bile acid production caused by mutations in the mitochondrial enzyme sterol 27-hydroxilase. This inborn error of bile acid metabolism results in lipid pathologic ...
Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi
(Elsevier, 2015-05-30)
Enzyme catalysis was applied to synthesize derivatives of three bile acids and their biological activity was evaluated as growth inhibitors of the protozoan Trypanosoma cruzi. Twelve mono-, diacetyl and ester derivatives ...
Lipase-Catalyzed Acetylation and Esterification of Bile Acids
(Humana Press, 2018)
In this chapter we describe the application of lipases as catalysts in reactions on a relevant family of steroids: the bile acids. Twenty three mono-, diacetyl and ester derivatives of deoxycholic-, chenodeoxycholic-, ...
Effects of ursodeoxycholic acid on conjugated bile acids and progesterone metabolites in serum and urine of patients with intrahepatic cholestasis of pregnancy
(Elsevier B.V., 1997)
Background/Aims and Methods: The mechanism(s) behind the effects of ursodeoxycholic acid on serum steroid sulphate profiles in patients with intrahepatic cholestasis of pregnancy is not clear. Conjugated progesterone ...
Differentiation of Xenarthra (Mammalia) species through the identification of their fecal bile acid patterns: An ecological tool
(Sociedad de Biología de Chile, 2010)
Bile acid profiles by capillary electrophoresis in intrahepatic cholestasis of pregnancy
(Portland Press, 2006-03)
ICP (Intrahepatic cholestasis of pregnancy) is characterized by pruritus and biochemical cholestasis, including raised SBAs (serum bile acids) and, usually, elevated aminotransferases levels. However, AHP (asymptomatic ...
Experimental Protoporphyria: Effect of bile acids on liver damage induced by griseofulvin
(Hindawi Publishing Corporation, 2015-01)
The effect of bile acids administration to an experimental mice model of Protoporphyria produced by griseofulvin (Gris) was investigated. The aim was to assess whether porphyrin excretion could be accelerated by bile acids ...
LC-MS/MS Method Applied to the Detection and Quantification of Ursodeoxycholic Acid Related Substances in Raw Material and Pharmaceutical Formulation
(David Publishing, 2018-04)
Abstract: Objective: To develop a highly sensitive LC-MS/MS (liquid chromatography-mass spectrometry/mass spectrometry)method applied to the detection and quantitation of UDCA (ursodeoxycholic acid) related substances such ...
Co-adsorbing effect of bile acids containing bulky amide groups at 3β-position on the photovoltaic performance in dye-sensitized solar cells
(2019)
Co-adsorbing molecules attain certain control in the surrounding of the dyes leading to enhanced efficiencies
mainly by affecting the recombination of the photogenerated electrons and aggregation of dyes. Bile acids ...