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Antibacterial and antitumorigenic properties of microcin E492, a poreforming bacteriocin
(2009)
Microcins are a family of low-molecular weight bacteriocins produced and secreted by Gram-negative bacteria. This review is focused on microcin E492, a pore-forming bacteriocin produced by Klebsiella pneumoniae RYC492 that ...
The expression of genes involved in microcin maturation regulates the production of active microcin E492
(2002)
The production of active microcin E492, a channel-forming bacteriocin, was studied in exponential and stationary phase. The structural gene for this bacteriocin (mceA) is transcribed in exponential as well as in stationary ...
Microcin e492, a channel-forming bacteriocin from klebsiella pneumoniae, induces apoptosis in some human cell lines
(NATIONAL ACADEMY OF SCIENCES, 2002)
Amyloid formation modulates the biological activity of a bacterial protein
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2005-07-22)
The aggregation of proteins into amyloid fibrils is the hallmark feature of a group of late-onset degenerative diseases including Alzheimer, Parkinson, and prion diseases. We report here that microcin E492, a peptide ...
Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines
(2002)
The cytotoxic effect of microcin E492, a low-molecular-mass channel-forming bacteriocin (7,887 Da) produced by a strain of Klebsiella pneumoniae, was characterized in HeLa cells. At low (5 microg/ml) and intermediate (10 ...