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Differential Expression of Monocarboxylate Transporter 1 and Ancillary Protein CD147 in Red Blood Cells of Show Jumping Horses
(2017-03-01)
We compare the expression levels of the lactate transporter complex consisting of the lactate transporter, monocarboxylate transporter 1 (MCT1), and its ancillary protein, cluster of differentiation 147 (CD147), in the ...
CD147 and MCT1-potential partners in bladder cancer aggressiveness and cisplatin resistance
(Wiley-Blackwell, 2015-11-01)
The relapsing and progressive nature of bladder tumors, and the heterogeneity in the response to cisplatin-containing regimens, are the major concerns in the care of urothelial bladder carcinoma (UBC) patients. The metabolic ...
The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer
(ELSEVIER SCI LTD, 2009)
The aim of the present work was to assess the role of monocarboxylate transporters (MCTs), namely MCT1 and MCT4 as well as MCT/CD147 co-expression in gastric tissues and evaluate their clinico-pathological significance in ...
CD147 overexpression allows an accurate discrimination of bladder cancer patients' prognosis
(Elsevier B.V., 2011-09-01)
Background: Urothelial bladder carcinoma (UBC) is a chemo-sensitive tumour, but the response to treatment is heterogeneous. CD 147 has been associated with chemotherapy resistance. We aimed to define tumours with an ...
Expressão dos transportadores de monocarboxilatos de equinos e cães
(Universidade Estadual Paulista (UNESP), 2017-11-13)
O principal mecanismo de transporte dos íons lactato e H+ em equinos e cães é o complexo transportador formado pelos transportadores de monocarboxilatos, isoformas 1 (MCT1) e 4 (MCT4) juntamente com a proteína auxiliar ...
Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147) is associated with low survival in patients with gastrointestinal stromal tumors (GISTs)
(SPRINGER/PLENUM PUBLISHERSNEW YORK, 2012)
Monocarboxylate transporters (MCTs) have been described to play an important role in cancer, but to date there are no reports on the significance of MCT expression in gastrointestinal stromal tumors (GISTs). The aim of the ...
Polymorphisms in candidate genes for athletic performance and quantification of MCT1 and CD147 in red blood cells of arabian and quarter horses
(Universidade Estadual Paulista (UNESP), 2016-10-19)
O transportador de monocarboxilato isoforma 1 (MCT1), presente na membrana das hemácias, e sua proteína auxiliar CD147 têm como função transportar H+ e lactato do plasma para dentro das hemácias, mantendo assim, a ...
Quantification of MCT1 and CD147 in Red Blood Cells of Arabian and Quarter Horses
(2016-08-01)
During anaerobic glycolysis for energy production, lactate and H+ ions accumulate in muscle fibers and pass into the blood stream. The monocarboxylate transporter isoform 1 (MCT1) and its ancillary protein cluster of ...