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Inhibitory effects of ascorbic acid, vitamin E, and vitamin B-complex on the biological activities induced by Bothrops venom

Oliveira, Carlos Henrique de Moura; Simão, Anderson Assaid; Marcussi, Silvana (Taylor & Francis, 2020)

Bothrops jararacussu (Jararacussu). Diet.

Universidade Estadual Paulista (Unesp) (2012-03-01)

Co-60 gamma irradiation prevents Bothrops jararacussu venom neurotoxicity and myotoxicity in isolated mouse neuromuscular junction

Universidade Estadual Paulista (Unesp); Instituto de Pesquisas Energéticas e Nucleares (IPEN) (Elsevier B.V., 2002-08-01)

The ability of gamma radiation from Co-60 (2000 Gy) to attenuate the toxic effects of Bothrops jararacussu venom was investigated on mouse neuromuscular preparations in vitro. A comparative study between the effects of ...

Purification, characterization and crystallization of Jararacussin-I, a fibrinogen-clotting enzyme isolated from the venom of Bothrops jararacussu

Universidade Estadual Paulista (Unesp); UNAERP (Elsevier B.V., 2002-09-01)

A fibrinogen-clotting enzyme, Jararacussin-I, was purified from the venom of Bothrops jararacussu by a combination of ion exchange chromatography using Resource 15S resin and affinity chromatography using Benzamidine ...

Purification and preliminary crystallographic analysis of a new Lys49-PLA2 from B-jararacussu

Universidade Estadual de Campinas (UNICAMP); Universidade Estadual Paulista (Unesp) (Mdpi Ag, 2008-05-01)

BjVIII is a new myotoxic Lys49-PLA2 isolated from Bothrops jararacussu venom that exhibits atypical effects on human platelet aggregation. To better understand the mode of action of BjVIII, crystallographic studies were ...

Structural and functional characterization of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) from Bothrops jararacussu snake venom

Universidade de São Paulo (USP); Univ Ribeirao Preto; Universidade Estadual Paulista (Unesp); Universidade Federal do Rio de Janeiro (UFRJ) (Elsevier B.V., 2002-08-15)

An acidic (pI similar to 4.5) phospholipase A(2) (BthA-I-PLA(2)) was isolated from Bothrops jararacussu snake venom by ion-exchange chromatography on a CM-Sepharose column followed by reverse phase chromatography on an ...

cDNA sequence and molecular modeling of a nerve growth factor from Bothrops jararacussu venomous gland

Univ Ribeirao Preto; Universidade de São Paulo (USP); Univ Amazonas; Universidade Estadual Paulista (Unesp) (Elsevier B.V., 2002-07-01)

The complete nucleotide sequence of a nerve growth factor precursor from Bothrops jararacussu snake (Bj-NGF) was determined by DNA sequencing of a clone from cDNA library prepared from the poly(A) + RNA of the venom gland ...

Neutralization of pharmacological and toxic activities of Bothrops jararacussu snake venom and isolated myotoxins by Serjania erecta methanolic extract and its fractions

Fernandes, R. S.; Costa, T. R.; Marcussi, S; Bernardes, C. P.; Menaldo, D. L.; Gonzaléz, Rodriguéz; Pereira, P. S.; Soares, A. M. (Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) - Câmpus de Botucatu, 2020)

A Catalytically Inactive Lys49 PLA2 Isoform from Bothrops jararacussu venom that Stimulates Insulin Secretion in Pancreatic Beta Cells

Universidade Estadual de Campinas (UNICAMP); Univ Mackenzie SP; Universidade Estadual Paulista (Unesp) (Bentham Science Publ Ltd, 2011-11-01)

A new secretory phospholipase A2 (sPLA2) isoform from Bothrops jararacussu venom (BjVIII) has been characterized by causing platelet aggregation, an absent activity in BthTx-I, Prtx-I and PrTx-II sPLA2s. According to our ...

Synthesis and evaluation of sesquiterpene lactone inhibitors of phospholipase A2 from Bothrops jararacussu

Alvarenga, E. S. de; Silva, S. A.; Barosa, L. C. A.; Demuner, A. J.; Parreira, A. G.; Ribeiro, R. I. M. A.; Marcussi, S.; Ferreira, J. M. S.; Resende, R. R.; Granjeiro, P. A.; Silva, J. A.; Soares, A. M.; Marangoni, S.; Silva, S. L. da (Elsevier, 2020)

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