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Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function
(FUTURE MEDICINE LTD, 2010)
Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the CNS, where it plays several pivotal roles in synaptic plasticity and neuronal survival. As a consequence, BDNF has become a key ...
Relação entre as alterações estruturais do cerebelo e os transtornos psiquiátricos
(Universidade Federal de São Paulo (UNIFESP), 2011-06-29)
Classically it was attributed to the cerebellum only functions regarding the control of movements, posture and balance. However, several studies have shown that the cerebellum also participates in the control of cognition, ...
Platelet GSK3B activity in patients with late-life depression: Marker of depressive episode severity and cognitive impairment?
(INFORMA HEALTHCARE, 2011)
Objective. Increased GSK3B activity has been reported as a state marker of major affective episodes in patients with depression and bipolar disorder. No study so far has addressed GSK3B activity in late-life depression. ...
The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis
(BLACKWELL PUBLISHING, 2008)
Purpose: As reported by several authors, angiotensin II (AngII) is a proinflammatory molecule that stimulates the release of inflammatory cytokines and activates nuclear factor kappa B (NF kappa B), being also associated ...