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Novel beta-Lactams
(Contexto, 2008-10-01)
The beta-lactam class constitutes the largest group of antimicrobial agents, which includes penicillins, cephalosporins, monobactams, and carbapenems. These compounds, which have in common the beta-lactam ring in their ...
Resistance to tetracycline and β-lactams and distribution of resistance markers in enteric microorganisms and pseudomonads isolated from the oral cavity
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2009-12-01)
This study evaluated the occurrence of enteric bacteria and pseudomonads resistant to tetracycline and beta-lactams in the oral cavity of patients exhibiting gingivitis (n=89); periodontitis (n=79), periodontally healthy ...
Structural Basis for the Interaction and Processing of beta-Lactam Antibiotics by L,D-Transpeptidase 3 (Ldt(Mt3)) from Mycobacterium tuberculosis
(Amer Chemical Soc, 2019-02-01)
Targeting Mycobacterium tuberculosis peptidoglycans with beta-lactam antibiotics represents a strategy to address increasing resistance to antitubercular drugs. beta-Lactams inhibit peptidoglycan synthases such as ...
Resistance to tetracycline and β-lactams and distribution of resistance markers in enteric microorganisms and pseudomonads isolated from the oral cavity
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2013)
Resistance to tetracycline and β-lactams and distribution of resistance markers in enteric microorganisms and pseudomonads isolated from the oral cavity
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2013)
Solid-phase Petasis multicomponent reaction for the generation of beta-lactams 3-substituted with non-proteinogenic alfa-amino acids
(Elsevier, 2013-07)
An efficient protocol for the rapid generation of libraries of biologically promising b-lactams is described. Key step is a solid-phase based multicomponent Petasis reaction
1,3-Dipolar cycloaddition of nitrile imines with alpha,beta-unsaturated lactones, thiolactones and lactams: synthesis of ring-fused pyrazoles
(PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2012)
Removal of beta-lactams antibiotics through zero-valent copper nanoparticles
(Journal of the Brazilian Chemical Society, 2019)
Effect of childhood pneumococcal vaccination and beta-lactam antibiotic use on the incidence of invasive pneumococcal disease in the adult population
Describe the incidence of invasive pneumococcal disease (IPD) in serotypes with reduced antibiotic sensitivity to penicillin (RAS-Pen) in adults over 59 years of age and its association with childhood anti-pneumococcal ...
Frequency of plasmid-mediated AmpC in Enterobacteriaceae isolated in a Brazilian Teaching Hospital
(Sociedade Brasileira de Microbiologia, 2013-01-01)
In Brazil, the presence of plasmid-mediated AmpC (pAmpC)-producing isolates has been sporadically reported. We evaluated the frequency of pAmpC among 133 Enterobacteriaceae clinical isolates. The blaCMY-2-like gene was ...