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Toxin-antitoxin systems and its biotechnological applications
(2014)
Toxin-antitoxin (TA) systems are important genetic modules composed by two elements: a toxin, that is always a protein, and an antitoxin, that can be a RNA or a protein and neutralizes the toxic effect of toxin. These ...
Study of the presence of the spores of Clostridium botulinum in honey in Brazil
(1999-07-01)
The isolation of Clostridium botulinum from honey samples is described. Botulism is characterized as an intoxication provoked by ingestion of contaminated foods with this toxin. Infant botulism happens by the ingestion of ...
Function inferences from a molecular structural model of bacterial ParE toxin
(2010)
Toxin-antitoxin (TA) systems contribute to plasmid stability by a mechanism that relies on the differential stabilities of the toxin and antitoxin proteins and leads to the killing of daughter bacteria that did not receive ...
Design and synthesis of peptides from bacterial ParE toxin as inhibitors of topoisomerases
(Elsevier France-editions Scientifiques Medicales Elsevier, 2012-08-01)
Toxin-antitoxin (TA) proteic systems encode a toxin and an antitoxin that regulate the growth and death of bacterial cells under various stress conditions. The ParE protein is a toxin that inhibits DNA gyrase activity and ...
Distribution of additional virulence factors related to adhesion and toxicity in Shiga toxin-producing Escherichia coli isolated from raw products in Argentina
(Wiley, 2013-04)
A total of 73 Shiga toxin-producing Escherichia coli (STEC) isolates, belonging to 25 serotypes and isolated from raw products in Argentina, were examined for the occurrence of genes responsible for bacterial adhesions to ...
Niche-specific association of Aeromonas ribotypes from human and environmental origin
(2003-01-30)
A total of 88 Aeromonas isolates from distinct locations and sources (39 from extraintestinal infections, 31 from diarrhoeic, ten from non-diarrhoeic faeces, all human, and eight from fresh water) were subjected to ...
Síntese, caracterização e estudos de interação de um análogo da antitoxina CcdA empregando fluorescência no estado estacionário
(Sociedade Brasileira de Química, 2010-01-01)
Toxin-antitoxin (TA) systems contribute to plasmid stability by a mechanism called post-segregational killing. The ccd was the first TA system to be discovered with CcdB being the toxin and CcdA the antitoxin. CcdA, an 8.3 ...
Characterization of an OrtT-like toxin of Salmonella enterica serovar Houten
(Springer, 2019-07-01)
The Escherichia coli GhoT/GhoS system is a type V toxin-antitoxin system in which the antitoxin GhoS cleaves the GhoT mRNA, controlling its translation. GhoT is a small hydrophobic protein that damages bacterial membranes. ...