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BRCA 1 and 2 gene expression in bitches (Canis lupus familiaris) mammary tumors and its association with clinical-pathological parametersExpresión del gen BRCA 1 y 2 en neoplasias mamarias de perras (Canis lupus familiaris) y su asociación con parámetros clínicopatológicos
(Universidad Centroccidental Lisandro Alvarado, 2023)
Determinación de una mutación en el gen BRCA1 en una familia que presenta cáncer de mama hereditario
(Sociedad Médica de Santiago, 2004)
Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors
(TAYLOR & FRANCIS INC, 2008)
Germline mutations in BRCA1 account for a low proportion of hereditary cases in diverse populations. Several efforts have been made to find new genes involved in the inheritance of breast cancer with no success until today. ...
Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors
Germline mutations in BRCA1 account for a low proportion of hereditary cases in diverse populations. Several efforts have been made to find new genes involved in the inheritance of breast cancer with no success until today. ...
Transcriptional Autoregulation by BRCA1
(American Association For Cancer Research, 2010-01)
The BRCA1 gene product plays numerous roles in regulating genome integrity. Its role in assembling supermolecular complexes in response to DNA damage has been extensively studied; however, much less is understood about its ...
Determination of a BRCA1 gene mutation in a family with hereditary breast cancer
(SOC MEDICA SANTIAGO, 2004)
Background: Breast cancer is the main cause of death among fore, the women between 40 and 55 years old, in whom the hereditary cases are common. Therefore molecular diagnosis of germ line initiations involved in breast ...
BRCA1 and BRCA2 analysis of argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin
(Springer, 2012-09)
Background: The spectrum of BRCA1/2 genetic variation in breast-ovarian cancer patients has been scarcely investigated outside Europe and North America, with few reports for South America, where Amerindian founder effects ...
BRCA1 loss induces GADD153-mediated doxorubicin resistance in prostate cancer
(American Association for Cancer Research, 2011-08)
BRCA1 plays numerous roles in the regulation of genome integrity and chemoresistance. Although BRCA1 interaction with key proteins involved in DNA repair is well known, its role as a coregulator in the transcriptional ...
Absence of the BRCA1 del (exons 9–12) mutation in breast/ovarian cancer families outside of Mexican Hispanics
(Breast Cancer Res Treat, 2009-03-31)
The frequency and spectrum of germ line mutations in the
high-penetrance breast cancer susceptibility genes BRCA1
and BRCA2 shows considerable variation by ethnic group.
Most genetic epidemiological studies of the BRCA ...