Most neurodegenerative diseases involve the accumulation of misfolded proteins in the nervous system. Impairment of protein degradation pathways such as autophagy is emerging as a consistent and transversal pathological ...

Biologic therapeutics are the medicines of the future and are destined to transform the approaches by which the causes and symptoms of diseases are cured and alleviated. These approaches will be accelerated through the ...

Several derivatives aminopyrazoles, which are a new class of synthetic insecticide agents, have shown biological activity against lepidopteran, such as Spodoptera frugiperda. The aim of this work was to assess the biological ...

The distribution of 5'-nucleotidase activity in pre-implantation mouse embryos is studied by means of a cytochemical method adapted from Uusitalo & Karnovsky (1977). The enzyme activity is detected from the 4-cell stage ...