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Chaperone-mediated autophagy-mechanisms and disease role
(Elsevier, 2021-01-01)
Autophagy is a process in which proteins and organelles are degraded via the lysosome to maintain or remodel cellular homeostasis. In mammals, three autophagic pathways have been described: macroautophagy (frequently ...
Pro-Tumoral Functions of Autophagy Receptors in the Modulation of Cancer Progression
(2021-02-01)
Cancer progression involves a variety of pro-tumorigenic biological processes including cell proliferation, migration, invasion, and survival. A cellular pathway implicated in these pro-tumorigenic processes is autophagy, ...
The CB1 cannabinoid receptor regulates autophagy in the tibialis anterior skeletal muscle in mice
(2023-12)
The endocannabinoid system (ECS) regulates energy metabolism, has been implicated in the pathogenesis of metabolic diseases and exerts its actions mainly through the type 1 cannabinoid receptor (CB1). Likewise, autophagy ...