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Analysis of thyroglobulin gene polymorphisms in patients with autoimmune thyroiditis
(Springer, 2010-06)
The autoimmune thyroid disease is a complex disorder caused by a combination of genetic susceptibility and environmental factors, which are believed to initiate the autoimmune response to thyroid antigens. Identification ...
Association of the TGrI29 microsatellite in thyroglobulin gene with autoimmune thyroiditis in a Argentinian population: a case–control study
(Humana Press, 2010-12)
Autoimmune thyroid disease (AITD) is a multifactorial disorder that involves a putative association with thyroid autoantigen-specific and immune regulatory genes, as well as environmental factors. The thyroglobulin gene ...
The role of regulatory T Cells in autoimmune orchitis
(Wiley Blackwell Publishing, Inc, 2018-12)
Regulatory T cells (Tregs) mediate tolerance to self-antigens maintaining immune homeostasis. Defects in the number and function of Tregs lead to aberrant immune responses to autologous components, thereby causing autoimmune ...
Waiting list registration and liver transplantation rates among patients with autoimmune liver disease: An 11-year trend analysis
(Oat, 2021-04)
Objectives: We aimed to analyze waiting list and liver transplantation trends for autoimmune liver disease in Argentina.Methods: We designed a population-based analysis of waitlisted or liver transplanted patients for ...
Untangling galectin-driven regulatory circuits in autoimmune inflammation
(Elsevier, 2018-04)
Although significant progress has been made in understanding the mechanisms implicated in the pathogenesis and resolution of autoimmune inflammation, studies aimed at identifying mediators of these pathways are necessary ...
Pathomechanisms of autoimmune based testicular inflammation
(Frontiers Media, 2020-09)
Infection and inflammation of the male reproductive tract are relevant causes of infertility. Inflammatory damage occurs in the special immunosuppressive microenvironment of the testis, a hallmark termed testicular immune ...
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases
(Elsevier Science, 2015-02)
Dendritic cells (DCs) play a key role in the activation of the immune response against pathogens, as well as in the modulation of peripheral tolerance to self-antigens (Ags). Furthermore, an imbalance in the activating/inhibitory ...
Autoimmune hepatitis-like disease in C57BL/6 mice infected with mouse hepatitis virus A59
(Elsevier Science, 2011)
Diazepam Inhibits Proliferation of Lymph Node Cells Isolated from Rats with Experimental Autoimmune Encephalomyelitis
(Karger, 2014-10)
Objective: Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease with similar-ities to human multiple sclerosis involving peripheral activa-tion of autoreactive T cells which infiltrate ...
Regulatory role of heat-shock proteins in autoimmune and inflammatory diseases
(Open Access Text, 2016-08-22)
Classically, molecular chaperones play a pivotal role in the maintenance of cellular proteostasis and thus, in the safeguarding of the cell homeostasis while reducing the deleterious effects of extracellular and intracellular ...