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Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: Evolution toward prospective theranostic approaches
(Ivyspring International Publisher, 2018)
© Ivyspring International Publisher. Cardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying ...
Incremental replacement of saturated fats by n 3 fatty acids in high-fat, high-cholesterol diets reduces elevated plasma lipid levels and arterial lipoprotein lipase, macrophages and atherosclerosis in LDLR / mice
(Elsevier, 2014)
Objective: Effects of progressive substitution of dietary n 3 fatty acids (FA) for saturated FA (SAT) on
modulating risk factors for atherosclerosis have not been fully defined. Our previous reports demonstrate
that SAT ...
SASH1, a new potential link between smoking and atherosclerosis
(Elsevier, 2015)
Objective: We have previously reported that SASH1 expression is increased in circulating human monocytes from smokers and was positively correlated with the number of carotid atherosclerotic plaques. The aim of this study ...
Clinical pharmacology and therapeutic use of antioxidant vitamins
(2007)
The clinical use of antioxidants has gained considerable interest during the last decade. It was suggested from epidemiological studies that diets high in fruits and vegetables might help decrease the risk of cardiovascular ...
Helicobacter pylori: A new cardiovascuar risk factor?
(2002)
There is increasing evidence that certain microbial agents may have an etiopathogenic role in the development of atherothrombosis. Helicobacter pylori, a bacterium that causes peptic ulcer disease, has been suggested as ...
Oxidative stress in the local and systemic events of apical periodontitis
(Frontiers Media SA, 2017)
Oxidative stress is involved in the pathogenesis of a variety of inflammatory disorders. Apical periodontitis (AP) usually results in the formation of an osteolytic apical lesion (AL) caused by the immune response to ...
Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases
(Bentham, 2015)
Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have
shown recent success. Both intravenous and oral administration have been investigated and
achieved different degrees of ...
Cardiovascular autophagy concepts, controversies, and perspectives
(Taylor and Francis Inc., 2013)
Despite recent scientific and technological advances, cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Autophagy, an evolutionarily ancient response to cellular stress, has been ...
Molecular mechanisms of autophagy in the cardiovascular system
(Lippincott Williams and Wilkins, 2015)
Autophagy is a catabolic recycling pathway triggered by various intra- or extracellular stimuli that
is conserved from yeast to mammals. During autophagy diverse cytosolic constituents are
enveloped by double-membrane ...
Regulation of the sodium-phosphate cotransporter Pit-1 and its role in vascular calcification
(2009)
Vascular calcification is caused by the deposition of basic calcium phosphate crystals in blood vessels, myocardium, and/or cardiac valves. Calcification decreases artery wall compliance, and arterial calcification is ...