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Production and Characterization of L-Asparaginases of Streptomyces Isolated from the Arauca Riverbank (Colombia)
(The Open Microbiology Journal, 2019-01-19)
Introduction:
L-asparaginase, is known as an anti-cancer agent, mainly used in acute lymphoblastic leukemia, which prevents the proliferation of tumor cells. This study shows that there are unexplored regions in Colombia ...
Production of L-asparaginase by Filamentous Fungi
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Therapeutic l-asparaginase: upstream, downstream and beyond
(2017-01-02)
l-asparaginase (l-asparagine amino hydrolase, E.C.3.5.1.1) is an enzyme clinically accepted as an antitumor agent to treat acute lymphoblastic leukemia and lymphosarcoma. It catalyzes l-asparagine (Asn) hydrolysis to ...
L-asparaginase and Biosurfactants Produced by Extremophile Yeasts from Antarctic Environments
(2020-04-01)
In this study, L-asparaginase and biosurfactants production by yeasts isolated from marine and terrestrial Antarctic environments was investigated. L-asparaginase production was determined by assessing enzyme activity and ...
Glutaminase-free L-asparaginase production by Leucosporidium muscorum isolated from Antarctic marine-sediment
(2020-01-01)
L-asparaginase (ASNase) is an essential drug in the treatment of acute lymphoblastic leukemia (ALL). Commercial bacterial ASNases increase patient survival, but the consequent immunological reactions remain a challenge. ...
A novel multiple reactor system for the long-term production of L-asparaginase by Penicillium sp. LAMAI 505
(2020-03-01)
In this paper a novel system of multiple reactors with immobilized cells (MRICs) to produce L-asparaginase by Penicillium sp. LAMAI 505 is presented. The effects of the number of associated reactors, nutrient composition, ...
CHEESE WHEY UTILIZATION FOR L-ASPARAGINASE PRODUCTION FROM ERWINIA-AROIDEAE NRRL B-138 IN PILOT-PLANT
(Inst Tecnologia ParanaCuritiba-paranaBrasil, 1993)